ENSMUSG00000020059


Mus musculus

Features
Gene ID: ENSMUSG00000020059
  
Biological name :Sycp3
  
Synonyms : Sycp3 / synaptonemal complex protein 3
  
Possible biological names infered from orthology : Q8IZU3
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 88459569
Gene end: 88473236
  
Corresponding Affymetrix probe sets: 10365627 (MoGene1.0st)   1449534_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020252
Ensembl peptide - ENSMUSP00000137704
Ensembl peptide - ENSMUSP00000137800
NCBI entrez gene - 20962     See in Manteia.
MGI - MGI:109542
RefSeq - NM_011517
RefSeq Peptide - NP_035647
swissprot - M0QWF4
swissprot - M0QW86
swissprot - A2RSE7
Ensembl - ENSMUSG00000020059
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sycp3ENSDARG00000013438Danio rerio
 SYCP3ENSGALG00000012766Gallus gallus
 SYCP3ENSG00000139351Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
1700013H16Rik / RIKEN cDNA 1700013H16 geneENSMUSG0000005472736
Xlr / P05531 / X-linked lymphocyte-regulatedENSMUSG0000005462630
3830403N18Rik / RIKEN cDNA 3830403N18 geneENSMUSG0000003112529
Xlr5b / X-linked lymphocyte-regulated 5BENSMUSG0000007247926
Gm20736ENSMUSG0000009399325
Gm28919ENSMUSG0000010124325
Xlr5a / X-linked lymphocyte-regulated 5AENSMUSG0000005832825
Gm20931ENSMUSG0000009457024
Gm28827ENSMUSG0000009992524
Gm21497ENSMUSG0000010072624
Gm21366ENSMUSG0000010391924
Gm20911ENSMUSG0000009989424
Gm20850ENSMUSG0000010090224
Gm35134ENSMUSG0000010337124
Gm30737ENSMUSG0000010419124
Gm20870ENSMUSG0000010053524
Gm21095ENSMUSG0000009515324
Gm20920ENSMUSG0000010048524
Gm20903ENSMUSG0000009978224
Gm20906ENSMUSG0000009985624


Protein motifs (from Interpro)
Interpro ID Name
 IPR006888  XLR/SYCP3/FAM9 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035093 spermatogenesis, exchange of chromosomal proteins IEA
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0000800 lateral element IEA
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Pafah1b1tm2Awb/Pafah1b1tm2Awb
Genetic Background: involves: 129S/SvEv * FVB/N * NIH Black Swiss

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pafah1b1tm2Awb/Pafah1b1tm2Awb
Genetic Background: involves: 129S/SvEv * FVB/N * NIH Black Swiss

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pafah1b1tm2Awb/Pafah1b1tm2Awb
Genetic Background: involves: 129S/SvEv * FVB/N * NIH Black Swiss

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pafah1b1tm2.2Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0010511 shortened PR interval "decrease in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011954 shortened PQ interval "decrease in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave" [MPD:Molly]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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