ENSMUSG00000020326


Mus musculus

Features
Gene ID: ENSMUSG00000020326
  
Biological name :Ccng1
  
Synonyms : Ccng1 / Cyclin-G1 / P51945
  
Possible biological names infered from orthology : P51959
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A5
Gene start: 40748552
Gene end: 40755311
  
Corresponding Affymetrix probe sets: 10385271 (MoGene1.0st)   1420827_a_at (Mouse Genome 430 2.0 Array)   1450016_at (Mouse Genome 430 2.0 Array)   1450017_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020576
NCBI entrez gene - 12450     See in Manteia.
MGI - MGI:102890
RefSeq - XM_011248706
RefSeq - NM_009831
RefSeq Peptide - NP_033961
swissprot - P51945
swissprot - Q5NC86
Ensembl - ENSMUSG00000020326
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccng1ENSDARG00000076667Danio rerio
 CCNG1ENSGALG00000001718Gallus gallus
 CCNG1ENSG00000113328Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccng2 / O08918 / Cyclin-G2 / Q16589*ENSMUSG0000002938552
Ccni / Q9Z2V9 / Cyclin-I / Q14094*ENSMUSG0000006301527


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR028860  Cyclin-G1
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000511 abnormal intestinal mucosa morphology "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fbn1tm2Rmz/Fbn1tm2Rmz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001658 increased mortality induced by gamma-irradiation "greater sensitivity to doses of ionizing radiation" [J:51834]
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Allelic Composition: Fbn1tm2Rmz/Fbn1tm2Rmz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002007 increased sensitivity to gamma-irradiation "increased incidence of cell death following high levels of gamma-irradiation" [J:51834]
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Allelic Composition: Fbn1tm2Rmz/Fbn1tm2Rmz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002053 decreased incidence of induced tumors "reduced frequency of tumor incidence induced by a carcinogen or mutagen" [J:56886]
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Allelic Composition: Sufutm1Rto/Sufutm1Rto
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002658 abnormal liver regeneration "deviation from the normal ability of liver to regenerate healthy tissue following partial hepatectomy" [il:Ira Lu , Mouse Genome Informatics Curator]
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Allelic Composition: Sufutm1Rto/Sufutm1Rto
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Sufutm1Rto/Sufutm1Rto
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0010264 increased hepatoma incidence "greater than the expected number of malignant tumors composed of neoplastic liver cells in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sufutm1Rto/Sufutm1Rto
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0010265 decreased hepatoma incidence "less than the expected number of malignant tumors composed of neoplastic liver cells in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sufutm1Rto/Sufutm1Rto
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020184 Mdm2 / P23804 / E3 ubiquitin-protein ligase Mdm2 / Q00987* / MDM2 proto-oncogene*  / complex / reaction
 ENSMUSG00000017843 Q60996 / Ppp2r5c / protein phosphatase 2, regulatory subunit B, gamma / Q13362* / protein phosphatase 2 regulatory subunit Bgamma*  / reaction / complex






 

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