ENSMUSG00000020590


Mus musculus

Features
Gene ID: ENSMUSG00000020590
  
Biological name :Snx13
  
Synonyms : Snx13 / sorting nexin 13
  
Possible biological names infered from orthology : Q9Y5W8
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: A3
Gene start: 35047186
Gene end: 35147479
  
Corresponding Affymetrix probe sets: 10395328 (MoGene1.0st)   1435251_at (Mouse Genome 430 2.0 Array)   1444141_at (Mouse Genome 430 2.0 Array)   1454938_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130182
Ensembl peptide - ENSMUSP00000152167
Ensembl peptide - ENSMUSP00000038430
NCBI entrez gene - 217463     See in Manteia.
MGI - MGI:2661416
RefSeq - XM_017315018
RefSeq - XM_006515064
RefSeq - XM_006515065
RefSeq - XM_017315016
RefSeq - XM_017315017
RefSeq - NM_001014973
RefSeq - XM_006515062
RefSeq Peptide - NP_001014973
swissprot - E9QNG6
swissprot - E9Q7T4
swissprot - A0A1Y7VKV2
Ensembl - ENSMUSG00000020590
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx13ENSDARG00000013828Danio rerio
 SNX13ENSGALG00000010840Gallus gallus
 SNX13ENSG00000071189Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snx25 / Q3ZT31 / Sorting nexin-25 / Q9H3E2*ENSMUSG0000003829122
Snx14 / Q8BHY8 / Sorting nexin-14 / Q9Y5W7*ENSMUSG0000003242219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR003114  Phox-associated domain
 IPR013937  Sorting nexin, C-terminal
 IPR016137  RGS domain
 IPR036305  RGS domain superfamily
 IPR036871  PX domain superfamily
 IPR037437  Sorting nexin-13, PX domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0001711 abnormal placenta 
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0001724 abnormal extraembryonic endoderm formation "malformation of the endoderm of the extraembryonic tissue that appears prior to gastrulation and performs critical functions during embryogenesis including nutrient uptake and transport from the mother to the embryo" [J:62628]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0003658 abnormal capillaries "malformation in the minute blood vessels that connect arterioles and venules" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96775]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0004259 small placenta "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0005033 abnormal trophoblast cells "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Map3k7tm1.1Mds/Map3k7tm1.1Mds
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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