ENSMUSG00000020677


Mus musculus

Features
Gene ID: ENSMUSG00000020677
  
Biological name :Ddx52
  
Synonyms : Ddx52 / Probable ATP-dependent RNA helicase DDX52 / Q8K301
  
Possible biological names infered from orthology : DExD-box helicase 52 / Q9Y2R4
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 83942062
Gene end: 83963088
  
Corresponding Affymetrix probe sets: 10379779 (MoGene1.0st)   1434607_at (Mouse Genome 430 2.0 Array)   1434608_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048802
NCBI entrez gene - 78394     See in Manteia.
MGI - MGI:1925644
RefSeq - NM_030096
RefSeq Peptide - NP_084372
swissprot - Q8K301
Ensembl - ENSMUSG00000020677
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx52ENSDARG00000100505Danio rerio
 DDX52ENSGALG00000005489Gallus gallus
 DDX52ENSG00000278053Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006364 rRNA processing IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Cisd2tm1a(EUCOMM)Wtsi/Cisd2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cisd2tm1a(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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