ENSMUSG00000020954


Mus musculus

Features
Gene ID: ENSMUSG00000020954
  
Biological name :Strn3
  
Synonyms : Q9ERG2 / striatin, calmodulin binding protein 3 / Strn3
  
Possible biological names infered from orthology : Q13033 / striatin 3
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: B3
Gene start: 51609632
Gene end: 51691897
  
Corresponding Affymetrix probe sets: 10400191 (MoGene1.0st)   1423535_at (Mouse Genome 430 2.0 Array)   1423536_at (Mouse Genome 430 2.0 Array)   1441266_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000013130
Ensembl peptide - ENSMUSP00000130184
NCBI entrez gene - 94186     See in Manteia.
MGI - MGI:2151064
RefSeq - XM_006516412
RefSeq - NM_001172098
RefSeq - NM_052973
RefSeq - XM_006516410
RefSeq - XM_006516411
RefSeq Peptide - NP_001165569
RefSeq Peptide - NP_443205
swissprot - Q9ERG2
swissprot - B2RQS1
Ensembl - ENSMUSG00000020954
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 strn3ENSDARG00000001729Danio rerio
 STRN3ENSGALG00000040464Gallus gallus
 STRN3ENSG00000196792Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Strn / O55106 / Striatin / O43815*ENSMUSG0000002407763
Strn4 / P58404 / Striatin-4 / Q9NRL3*ENSMUSG0000003037453
Plrg1 / Q922V4 / Pleiotropic regulator 1 / O43660*ENSMUSG0000002799814


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR013258  Striatin, N-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0070016 armadillo repeat domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rpgrip1ltm1a(EUCOMM)Wtsi/Rpgrip1ltm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Rpgrip1ltm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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