ENSMUSG00000024077


Mus musculus

Features
Gene ID: ENSMUSG00000024077
  
Biological name :Strn
  
Synonyms : O55106 / Striatin / Strn
  
Possible biological names infered from orthology : O43815
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E3
Gene start: 78649913
Gene end: 78737196
  
Corresponding Affymetrix probe sets: 10452918 (MoGene1.0st)   1422036_at (Mouse Genome 430 2.0 Array)   1455022_at (Mouse Genome 430 2.0 Array)   1455156_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024881
Ensembl peptide - ENSMUSP00000117663
Ensembl peptide - ENSMUSP00000120830
NCBI entrez gene - 268980     See in Manteia.
MGI - MGI:1333757
RefSeq - XM_006524357
RefSeq - NM_011500
RefSeq Peptide - NP_035630
swissprot - F6Z700
swissprot - O55106
swissprot - F8WH41
Ensembl - ENSMUSG00000024077
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 strnENSDARG00000100011Danio rerio
 STRNENSGALG00000010580Gallus gallus
 STRNENSG00000115808Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Strn3 / Q9ERG2 / striatin, calmodulin binding protein 3 / Q13033* / striatin 3*ENSMUSG0000002095464
Strn4 / P58404 / Striatin-4 / Q9NRL3*ENSMUSG0000003037451
Plrg1 / Q922V4 / Pleiotropic regulator 1 / O43660*ENSMUSG0000002799814


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR013258  Striatin, N-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0070016 armadillo repeat domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002666 increased circulating aldosterone level "increased blood concentration of this hormone, secreted by the adrenal cortex, in the bloodstream; regulates sodium conservation and potassium secretion in the distal renal tubule" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Adam17tm1.1Bbl/Adam17tm1.1Bbl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0002842 increased blood pressure "increased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Adam17tm1.1Bbl/Adam17tm1.1Bbl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Adam17tm1.1Bbl/Adam17tm1.1Bbl
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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