ENSMUSG00000021360


Mus musculus

Features
Gene ID: ENSMUSG00000021360
  
Biological name :Gcnt2
  
Synonyms : Gcnt2 / N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase / P97402
  
Possible biological names infered from orthology : glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) / Q8N0V5
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.3
Gene start: 40859754
Gene end: 40960892
  
Corresponding Affymetrix probe sets: 10404702 (MoGene1.0st)   1421415_s_at (Mouse Genome 430 2.0 Array)   1425503_at (Mouse Genome 430 2.0 Array)   1430826_s_at (Mouse Genome 430 2.0 Array)   1437607_at (Mouse Genome 430 2.0 Array)   1438660_at (Mouse Genome 430 2.0 Array)   1450238_at (Mouse Genome 430 2.0 Array)   1451733_at (Mouse Genome 430 2.0 Array)   1453674_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070942
Ensembl peptide - ENSMUSP00000153207
Ensembl peptide - ENSMUSP00000153363
Ensembl peptide - ENSMUSP00000066467
Ensembl peptide - ENSMUSP00000105820
NCBI entrez gene - 14538     See in Manteia.
MGI - MGI:1100870
RefSeq - NM_023887
RefSeq - NM_008105
RefSeq - NM_133219
RefSeq Peptide - NP_076376
RefSeq Peptide - NP_573482
RefSeq Peptide - NP_032131
swissprot - Q7TPQ8
swissprot - Q9D2A8
swissprot - A0A286YDC7
swissprot - P97402
swissprot - Q6T5E4
Ensembl - ENSMUSG00000021360
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCNT2ENSGALG00000012773Gallus gallus
 GCNT2ENSG00000111846Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gcnt3 / Q5JCT0 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 / O95395* / glucosaminyl (N-acetyl) transferase 3, mucin type*ENSMUSG0000003222639
Gcnt7 / Q3V3K7 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 / Q6ZNI0* / glucosaminyl (N-acetyl) transferase family member 7*ENSMUSG0000007456939
Gcnt4 / E9Q649 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 / Q9P109* / glucosaminyl (N-acetyl) transferase 4, core 2*ENSMUSG0000009138738
Gcnt1 / Q09324 / Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase / Q02742* / glucosaminyl (N-acetyl) transferase 1, core 2*ENSMUSG0000003884336
Xylt1 / xylosyltransferase 1 / Q86Y38*ENSMUSG0000003065723
Xylt2 / Q9EPL0 / xylosyltransferase II / Q9H1B5* / xylosyltransferase 2*ENSMUSG0000002086821


Protein motifs (from Interpro)
Interpro ID Name
 IPR003406  Glycosyl transferase, family 14


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation ISO
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010608 posttranscriptional regulation of gene expression IMP
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0010812 negative regulation of cell-substrate adhesion ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion ISO
 biological_processGO:0036438 maintenance of lens transparency ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity ISO
 molecular_functionGO:0008375 acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002015 epithelioid cysts "abnormal membraneous sacs appearing in an epithelium" [J:51296]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005553 increased circulating creatinine level "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009640 abnormal renal tubule epithelium morphology "any structural anomaly of the cellular avascular layer of the renal tubule luminar surfaces" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptgs1tm1Unc/Ptgs1tm1Unc,Oxttm1Ljm/Oxttm1Ljm
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr