Manteia

ENSMUSG00000021639

Mus musculus

Features

Gene ID:	ENSMUSG00000021639

Biological name :	Gtf2h2

Synonyms :	Gtf2h2 / Q9JIB4 / ral transcription factor IIH subunit 2

Possible biological names infered from orthology :	general transcription factor IIH subunit 2 / GTF2H2C / GTF2H2 family member C / Q13888 / Q6P1K8

Species:	Mus musculus

Chr. number:	13
Strand:	-1
Band:	D1
Gene start:	100460218
Gene end:	100492579

Corresponding Affymetrix probe sets:	10411646 (MoGene1.0st) 1450701_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000064590 Ensembl peptide - ENSMUSP00000065228 Ensembl peptide - ENSMUSP00000138108 Ensembl peptide - ENSMUSP00000138748 NCBI entrez gene - 23894 See in Manteia. MGI - MGI:1345669 RefSeq - XM_006517662 RefSeq - NM_022011 RefSeq - XM_006517660 RefSeq Peptide - NP_071294 swissprot - Q91YN8 swissprot - Q9JIB4 swissprot - S4R2R0 swissprot - Q8C5I2 Ensembl - ENSMUSG00000021639

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR002035	von Willebrand factor, type A
IPR004595	TFIIH C1-like domain
IPR007198	Ssl1-like
IPR012170	TFIIH subunit Ssl1/p44
IPR013087	Zinc finger C2H2-type
IPR036465	von Willebrand factor A-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002031	G-protein coupled receptor internalization	ISO
biological_process	GO:0006281	DNA repair	IEA
biological_process	GO:0006289	nucleotide-excision repair	IEA
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
biological_process	GO:0006357	regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0006366	transcription by RNA polymerase II	ISS
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0006974	cellular response to DNA damage stimulus	IEA
cellular_component	GO:0000438	core TFIIH complex portion of holo TFIIH complex	ISO
cellular_component	GO:0000439	core TFIIH complex	IEA
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005669	transcription factor TFIID complex	ISO
cellular_component	GO:0005675	holo TFIIH complex	IBA
cellular_component	GO:0016607	nuclear speck	ISO
molecular_function	GO:0003676	nucleic acid binding	IBA
molecular_function	GO:0004672	protein kinase activity	ISS
molecular_function	GO:0008094	DNA-dependent ATPase activity	ISS
molecular_function	GO:0008270	zinc ion binding	IEA
molecular_function	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	ISO
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0047485	protein N-terminus binding	ISO

Pathways (from Reactome)

Pathway description

Formation of RNA Pol II elongation complex

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr