ENSMUSG00000021646


Mus musculus

Features
Gene ID: ENSMUSG00000021646
  
Biological name :Mccc2
  
Synonyms : Mccc2 / Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial / Q3ULD5
  
Possible biological names infered from orthology : methylcrotonoyl-CoA carboxylase 2 / Q9HCC0
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: D1
Gene start: 99948530
Gene end: 100015639
  
Corresponding Affymetrix probe sets: 10411532 (MoGene1.0st)   1428021_at (Mouse Genome 430 2.0 Array)   1432472_a_at (Mouse Genome 430 2.0 Array)   1454840_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022148
Ensembl peptide - ENSMUSP00000152799
Ensembl peptide - ENSMUSP00000152781
NCBI entrez gene - 78038     See in Manteia.
MGI - MGI:1925288
RefSeq - NM_030026
RefSeq Peptide - NP_084302
swissprot - A0A1Y7VK60
swissprot - B2RUK5
swissprot - Q3ULD5
swissprot - Q6PD20
Ensembl - ENSMUSG00000021646
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mccc2ENSDARG00000017571Danio rerio
 ENSGALG00000002529Gallus gallus
 MCCC2ENSG00000131844Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pccb / Q99MN9 / Propionyl-CoA carboxylase beta chain, mitochondrial / P05166* / propionyl-CoA carboxylase beta subunit*ENSMUSG0000003252728


Protein motifs (from Interpro)
Interpro ID Name
 IPR011762  Acetyl-coenzyme A carboxyltransferase, N-terminal
 IPR011763  Acetyl-coenzyme A carboxyltransferase, C-terminal
 IPR029045  ClpP/crotonase-like domain superfamily
 IPR034733  Acetyl-CoA carboxylase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006552 leucine catabolic process IEA
 biological_processGO:0015936 coenzyme A metabolic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix ISO
 cellular_componentGO:1905202 methylcrotonoyl-CoA carboxylase complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004485 methylcrotonoyl-CoA carboxylase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Biotin transport and metabolism
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021646 Mccc2 / Q3ULD5 / Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial / Q9HCC0* / methylcrotonoyl-CoA carboxylase 2*  / complex
 ENSMUSG00000027709 Mccc1 / Q99MR8 / Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial / Q96RQ3* / methylcrotonoyl-CoA carboxylase 1*  / complex
 ENSMUSG00000040820 Hlcs / Q920N2 / holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) / P50747* / holocarboxylase synthetase*  / reaction






 

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