ENSMUSG00000022019


Mus musculus

Features
Gene ID: ENSMUSG00000022019
  
Biological name :Tdrd3
  
Synonyms : Q91W18 / Tdrd3 / Tudor domain-containing protein 3
  
Possible biological names infered from orthology : Q9H7E2 / tudor domain containing 3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: E1
Gene start: 87416639
Gene end: 87545504
  
Corresponding Affymetrix probe sets: 10416709 (MoGene1.0st)   1434869_at (Mouse Genome 430 2.0 Array)   1441496_at (Mouse Genome 430 2.0 Array)   1451545_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126189
Ensembl peptide - ENSMUSP00000126212
Ensembl peptide - ENSMUSP00000129019
Ensembl peptide - ENSMUSP00000131542
NCBI entrez gene - 219249     See in Manteia.
MGI - MGI:2444023
RefSeq - XM_011245039
RefSeq - NM_001253755
RefSeq - NM_172605
RefSeq - XM_006518909
RefSeq - XM_006518910
RefSeq - XM_006518911
RefSeq - XM_006518912
RefSeq Peptide - NP_001240684
RefSeq Peptide - NP_766193
swissprot - Q91W18
swissprot - F6ZI20
Ensembl - ENSMUSG00000022019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tdrd3ENSDARG00000025421Danio rerio
 TDRD3ENSGALG00000016936Gallus gallus
 TDRD3ENSG00000083544Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rmi1 / Q9D4G9 / RecQ-mediated genome instability protein 1 / Q9H9A7* / RecQ mediated genome instability 1*ENSMUSG0000003536714


Protein motifs (from Interpro)
Interpro ID Name
 IPR002999  Tudor domain
 IPR009060  UBA-like superfamily
 IPR010304  Survival motor neuron
 IPR013894  RecQ mediated genome instability protein, N-terminal
 IPR015940  Ubiquitin-associated domain
 IPR033472  RecQ mediated genome instability protein, DUF1767


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0035145 exon-exon junction complex ISS
 molecular_functionGO:0003682 chromatin binding ISS
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0035064 methylated histone binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002144 abnormal B lymphocyte development "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Tg(Pou5f1-cre/ERT2)#Ysa/0
Genetic Background: involves: 129S6/SvEvTac

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Tg(Pou5f1-cre/ERT2)#Ysa/0
Genetic Background: involves: 129S6/SvEvTac

 MP:0008866 chromosomal instability "abnormalities of DNA metabolism, DNA repair, cell-cycle governance, or control of apoptosis that increase the probability that whole chromosomes or pieces of chromosomes are gained or lost during cell division, resulting in an imbalance in the number of chromosomes per cell (aneuploidy) and an enhanced rate of loss of heterozygosity" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:12446840]
Show

Allelic Composition: Smad4tm2.1Cxd/Smad4tm2.1Cxd,Tg(Pou5f1-cre/ERT2)#Ysa/0
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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