ENSMUSG00000022024


Mus musculus

Features
Gene ID: ENSMUSG00000022024
  
Biological name :Sugt1
  
Synonyms : Q9CX34 / SGT1 homolog, MIS12 kinetochore complex assembly cochaperone / Sugt1
  
Possible biological names infered from orthology : Q9Y2Z0
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D3
Gene start: 79587691
Gene end: 79635196
  
Corresponding Affymetrix probe sets: 10416666 (MoGene1.0st)   1426424_at (Mouse Genome 430 2.0 Array)   1426425_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052942
NCBI entrez gene - 67955     See in Manteia.
MGI - MGI:1915205
RefSeq - NM_026474
RefSeq Peptide - NP_080750
swissprot - Q9CX34
Ensembl - ENSMUSG00000022024
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sugt1ENSDARG00000100083Danio rerio
 SUGT1ENSGALG00000016946Gallus gallus
 SUGT1ENSG00000165416Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR007699  SGS domain
 IPR008978  HSP20-like chaperone
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0043947 positive regulation by host of symbiont catalytic activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010769 abnormal survival "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: F3tm1Fct/F3tm1Fct
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Rad9atm1.1(KOMP)Wtsi/Rad9atm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Rad9atm1.1(KOMP)Wtsi/Bay

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: F3tm1Fct/F3tm1Fct
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023944 P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*  / complex / reaction
 ENSMUSG00000032691 Nlrp3 / Q8R4B8 / NACHT, LRR and PYD domains-containing protein 3 / Q96P20* / NLR family pyrin domain containing 3*  / complex / reaction






 

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