ENSG00000165416


Homo sapiens

Features
Gene ID: ENSG00000165416
  
Biological name :SUGT1
  
Synonyms : Q9Y2Z0 / SGT1 homolog, MIS12 kinetochore complex assembly cochaperone / SUGT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q14.3
Gene start: 52652709
Gene end: 52700909
  
Corresponding Affymetrix probe sets: 223329_x_at (Human Genome U133 Plus 2.0 Array)   223330_s_at (Human Genome U133 Plus 2.0 Array)   224309_s_at (Human Genome U133 Plus 2.0 Array)   228045_at (Human Genome U133 Plus 2.0 Array)   244368_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308067
Ensembl peptide - ENSP00000367208
NCBI entrez gene - 10910     See in Manteia.
OMIM - 604098
RefSeq - XM_017020368
RefSeq - NM_001130912
RefSeq - NM_001320831
RefSeq - NM_006704
RefSeq - XM_011534893
RefSeq - XM_017020365
RefSeq - XM_017020366
RefSeq - XM_017020367
RefSeq - XM_011534891
RefSeq Peptide - NP_001307760
RefSeq Peptide - NP_006695
RefSeq Peptide - NP_001124384
swissprot - Q9Y2Z0
Ensembl - ENSG00000165416
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sugt1ENSDARG00000100083Danio rerio
 SUGT1ENSGALG00000016946Gallus gallus
 Sugt1ENSMUSG00000022024Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR007699  SGS domain
 IPR008978  HSP20-like chaperone
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle TAS
 biological_processGO:0031647 regulation of protein stability IDA
 biological_processGO:0043947 positive regulation by host of symbiont catalytic activity IDA
 cellular_componentGO:0000151 ubiquitin ligase complex TAS
 cellular_componentGO:0000776 kinetochore TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
The NLRP3 inflammasome


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000096384 P08238 / HSP90AB1 / heat shock protein 90 alpha family class B member 1  / - / reaction / complex
 ENSG00000137752 CASP1 / P29466 / caspase 1  / complex / reaction
 ENSG00000103490 PYCARD / Q9ULZ3 / PYD and CARD domain containing  / reaction / complex
 ENSG00000165416 SUGT1 / Q9Y2Z0 / SGT1 homolog, MIS12 kinetochore complex assembly cochaperone  / -
 ENSG00000162711 NLRP3 / Q96P20 / NLR family pyrin domain containing 3  / reaction / - / complex
 ENSG00000142192 APP / P05067 / amyloid beta precursor protein  / - / complex






 

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