ENSMUSG00000022201


Mus musculus

Features
Gene ID: ENSMUSG00000022201
  
Biological name :Zfr
  
Synonyms : O88532 / Zfr / zinc finger RNA binding protein
  
Possible biological names infered from orthology : Q96KR1
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: A1
Gene start: 12117831
Gene end: 12185683
  
Corresponding Affymetrix probe sets: 10423134 (MoGene1.0st)   1419650_at (Mouse Genome 430 2.0 Array)   1443002_at (Mouse Genome 430 2.0 Array)   1443357_at (Mouse Genome 430 2.0 Array)   1444096_at (Mouse Genome 430 2.0 Array)   1449552_at (Mouse Genome 430 2.0 Array)   1458450_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117207
Ensembl peptide - ENSMUSP00000119251
Ensembl peptide - ENSMUSP00000119524
Ensembl peptide - ENSMUSP00000114992
Ensembl peptide - ENSMUSP00000118911
NCBI entrez gene - 22763     See in Manteia.
MGI - MGI:1341890
RefSeq - XM_017316589
RefSeq - NM_011767
RefSeq - XM_006520057
RefSeq - XM_006520058
RefSeq - XM_006520059
RefSeq - XM_017316588
RefSeq Peptide - NP_035897
swissprot - O88532
swissprot - F6RTK9
swissprot - F6V459
swissprot - F6QJP7
swissprot - D3Z5G4
Ensembl - ENSMUSG00000022201
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfrENSDARG00000027109Danio rerio
 ENSGALG00000034488Gallus gallus
 ENSGALG00000003235Gallus gallus
 ZFRENSG00000056097Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfr2 / zinc finger RNA binding protein 2 / Q9UPR6*ENSMUSG0000003494935
Ilf3 / Q9Z1X4 / Interleukin enhancer-binding factor 3 / Q12906*ENSMUSG0000003217818
Strbp / Q91WM1 / spermatid perinuclear RNA binding protein / Q96SI9*ENSMUSG0000002691517
Ilf2 / Q9CXY6 / Interleukin enhancer-binding factor 2 / Q12905*ENSMUSG000000010169


Protein motifs (from Interpro)
Interpro ID Name
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger
 IPR006561  DZF domain
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001695 abnormal gastrulation "anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011186 abnormal visceral endoderm morphology "any structural anomaly of the primitive endoderm-derived tissue which remains in contact with and surrounds the extra-embryonic ectoderm and the epiblast and provides signals for the differentiation and patterning of the epiblast; a small number of visceral endoderm cells also contribute to the endoderm of the embryonic gut" [PMID:21123814]
Show

Allelic Composition: Nr2e1tm1Rtyu/Nr2e1tm1Rtyu
Genetic Background: Not Specified

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

Allelic Composition: Zfrtm1Reb/Zfrtm1Reb
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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