ENSMUSG00000026915


Mus musculus

Features
Gene ID: ENSMUSG00000026915
  
Biological name :Strbp
  
Synonyms : Q91WM1 / spermatid perinuclear RNA binding protein / Strbp
  
Possible biological names infered from orthology : Q96SI9
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 37483228
Gene end: 37703859
  
Corresponding Affymetrix probe sets: 10482177 (MoGene1.0st)   10482181 (MoGene1.0st)   1421125_at (Mouse Genome 430 2.0 Array)   1426411_a_at (Mouse Genome 430 2.0 Array)   1442465_s_at (Mouse Genome 430 2.0 Array)   1452061_s_at (Mouse Genome 430 2.0 Array)   1455146_at (Mouse Genome 430 2.0 Array)   1457218_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139145
Ensembl peptide - ENSMUSP00000122263
Ensembl peptide - ENSMUSP00000144874
Ensembl peptide - ENSMUSP00000028279
Ensembl peptide - ENSMUSP00000072047
Ensembl peptide - ENSMUSP00000120163
NCBI entrez gene - 20744     See in Manteia.
MGI - MGI:104626
RefSeq - XM_017316823
RefSeq - XM_011239046
RefSeq - XM_011239047
RefSeq - XM_017316819
RefSeq - XM_017316820
RefSeq - XM_017316821
RefSeq - XM_017316822
RefSeq - NM_001355259
RefSeq - NM_001355260
RefSeq - NM_009261
RefSeq - XM_011239043
RefSeq - XM_011239044
RefSeq - XM_011239045
RefSeq Peptide - NP_033287
RefSeq Peptide - NP_001342188
RefSeq Peptide - NP_001342189
swissprot - A2BH83
swissprot - Q91WM1
swissprot - A2BH82
Ensembl - ENSMUSG00000026915
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 strbpENSDARG00000021455Danio rerio
 STRBPENSGALG00000029927Gallus gallus
 STRBPENSG00000165209Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ilf3 / Q9Z1X4 / Interleukin enhancer-binding factor 3 / Q12906*ENSMUSG0000003217860
Zfr / O88532 / zinc finger RNA binding protein / Q96KR1*ENSMUSG0000002220128
Zfr2 / zinc finger RNA binding protein 2 / Q9UPR6*ENSMUSG0000003494924
Ilf2 / Q9CXY6 / Interleukin enhancer-binding factor 2 / Q12905*ENSMUSG0000000101613


Protein motifs (from Interpro)
Interpro ID Name
 IPR006561  DZF domain
 IPR014720  Double-stranded RNA-binding domain
 IPR030446  Spermatid perinuclear RNA-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0007638 mechanosensory behavior IMP
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0003727 single-stranded RNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000904 abnormal superior colliculus "dysmorphology or disorganization of the paired superior eminence of the mesencephalic tectum that is involved in auditory processing" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001380 male reduced copulation without impotence "males do not initiate sexual behavior as scored by the presence of copulation plugs (not due to infertility)" [J:57125]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0011750 abnormal seminiferous tubule epithelium morphology "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]
Show

Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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