ENSMUSG00000022205


Mus musculus

Features
Gene ID: ENSMUSG00000022205
  
Biological name :Sub1
  
Synonyms : Activated RNA polymerase II transcriptional coactivator p15 / P11031 / Sub1
  
Possible biological names infered from orthology : P53999 / SUB1 homolog, transcriptional regulator
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: A1
Gene start: 11981339
Gene end: 11996983
  
Corresponding Affymetrix probe sets: 10427807 (MoGene1.0st)   1422692_at (Mouse Genome 430 2.0 Array)   1422693_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022816
Ensembl peptide - ENSMUSP00000106130
NCBI entrez gene - 20024     See in Manteia.
MGI - MGI:104811
RefSeq - XM_006520042
RefSeq - NM_011294
RefSeq Peptide - NP_035424
swissprot - P11031
Ensembl - ENSMUSG00000022205
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sub1aENSDARG00000053446Danio rerio
 sub1bENSDARG00000007720Danio rerio
 ENSGALG00000034905Gallus gallus
 SUB1ENSGALG00000003248Gallus gallus
 SUB1ENSG00000113387Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003173  Transcriptional coactivator p15 (PC4)
 IPR009044  ssDNA-binding transcriptional regulator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IBA
 biological_processGO:0060395 SMAD protein signal transduction IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005667 transcription factor complex IBA
 cellular_componentGO:0005730 nucleolus ISO
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding ISO
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0042802 identical protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,Trmutm1Tomik/Trmutm1Tomik
Genetic Background: involves: C57BL/6 * DBA

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,Trmutm1Tomik/Trmutm1Tomik
Genetic Background: involves: C57BL/6 * DBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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