Manteia

ENSMUSG00000022761

Mus musculus

Features

Gene ID:	ENSMUSG00000022761

Biological name :	Lztr1

Synonyms :	Lztr1 / Mus musculus leucine-zipper-like transcriptional regulator, 1 (Lztr1), transcript variant 2, mRNA. / Q9CQ33

Possible biological names infered from orthology :	leucine zipper like transcription regulator 1 / Q8N653

Species:	Mus musculus

Chr. number:	16
Strand:	1
Band:	A3
Gene start:	17508968
Gene end:	17526331

Corresponding Affymetrix probe sets:	10434029 (MoGene1.0st) 1445461_at (Mouse Genome 430 2.0 Array) 1450927_at (Mouse Genome 430 2.0 Array) 1455928_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000023444 NCBI entrez gene - 66863 See in Manteia. MGI - MGI:1914113 RefSeq - XM_017317121 RefSeq - NM_001331226 RefSeq - NM_025808 RefSeq - XM_017317118 RefSeq - XM_017317119 RefSeq - XM_017317120 RefSeq - XM_006522476 RefSeq - XM_006522477 RefSeq Peptide - NP_080084 RefSeq Peptide - NP_001318155 swissprot - Q9CQ33 Ensembl - ENSMUSG00000022761

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q6PAR0 / Klhdc10 / Kelch domain-containing protein 10 / Q6PID8* / kelch domain containing 10*	ENSMUSG00000029775	14
Hcfc1 / Q61191 / Host cell factor 1 HCF N-terminal chain 1 HCF N-terminal chain 2 HCF N-terminal chain 3 HCF N-terminal chain 4 HCF N-terminal chain 5 HCF N-terminal chain 6 HCF C-terminal c...	ENSMUSG00000031386	14
Hcfc2 / host cell factor C2 / Q9Y5Z7*	ENSMUSG00000020246	13
Klhdc1 / Q80YG3 / Kelch domain-containing protein 1 / Q8N7A1* / kelch domain containing 1*	ENSMUSG00000051890	10
Klhdc2 / Q4G5Y1 / Kelch domain-containing protein 2 / Q9Y2U9* / kelch domain containing 2*	ENSMUSG00000020978	9
Q8VCH5 / Rabepk / Rab9 effector protein with kelch motifs / Q7Z6M1*	ENSMUSG00000070953	9
Klhdc3 / kelch domain containing 3 / Q9BQ90*	ENSMUSG00000063576	9

Protein motifs (from Interpro)

Interpro ID	Name
IPR000210	BTB/POZ domain
IPR006652	Kelch repeat type 1
IPR011333	SKP1/BTB/POZ domain superfamily
IPR011498	Kelch repeat type 2
IPR015915	Kelch-type beta propeller

Gene Ontology (GO)

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002968	increased circulating alkaline phosphatase level	"elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Lta^{tm1.1(KOMP)Vlcg}/Lta^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Lta^{tm1.1(KOMP)Vlcg}/Ucd
MP:0010067	increased red blood cell distribution width	"higher than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]	Show Allelic Composition: Lta^{tm1.1(KOMP)Vlcg}/Lta^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Lta^{tm1.1(KOMP)Vlcg}/Ucd
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Jam3^{tm1.1(KOMP)Vlcg}/Jam3^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Jam3^{tm1.1(KOMP)Vlcg}/J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr