ENSMUSG00000023019


Mus musculus

Features
Gene ID: ENSMUSG00000023019
  
Biological name :Gpd1
  
Synonyms : glycerol-3-phosphate dehydrogenase 1 (soluble) / Gpd1 / P13707
  
Possible biological names infered from orthology : glycerol-3-phosphate dehydrogenase 1 / P21695
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F1
Gene start: 99717515
Gene end: 99725005
  
Corresponding Affymetrix probe sets: 10426812 (MoGene1.0st)   1416204_at (Mouse Genome 430 2.0 Array)   1439396_x_at (Mouse Genome 430 2.0 Array)   1448249_at (Mouse Genome 430 2.0 Array)   1456732_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125164
Ensembl peptide - ENSMUSP00000023760
NCBI entrez gene - 14555     See in Manteia.
MGI - MGI:95679
RefSeq - NM_010271
RefSeq Peptide - NP_034401
swissprot - E0CXN5
swissprot - P13707
Ensembl - ENSMUSG00000023019
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpd1aENSDARG00000043701Danio rerio
 gpd1bENSDARG00000043180Danio rerio
 GPD1ENSG00000167588Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpd1l / Q3ULJ0 / glycerol-3-phosphate dehydrogenase 1-like / Q8N335*ENSMUSG0000005062772


Protein motifs (from Interpro)
Interpro ID Name
 IPR006109  Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal
 IPR006168  Glycerol-3-phosphate dehydrogenase, NAD-dependent
 IPR008927  6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
 IPR011128  Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal
 IPR013328  6-phosphogluconate dehydrogenase, domain 2
 IPR017751  Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006072 glycerol-3-phosphate metabolic process IEA
 biological_processGO:0006094 gluconeogenesis IMP
 biological_processGO:0006116 NADH oxidation IEA
 biological_processGO:0006127 glycerophosphate shuttle IMP
 biological_processGO:0006734 NADH metabolic process IEA
 biological_processGO:0045821 positive regulation of glycolytic process IMP
 biological_processGO:0046168 glycerol-3-phosphate catabolic process IEA
 biological_processGO:0046486 glycerolipid metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071320 cellular response to cAMP IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0009331 glycerol-3-phosphate dehydrogenase complex IEA
 molecular_functionGO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity IEA
 molecular_functionGO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cited2tm1.2Dunw/Cited2tm1.2Dunw
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023019 Gpd1 / P13707 / glycerol-3-phosphate dehydrogenase 1 (soluble) / P21695* / glycerol-3-phosphate dehydrogenase 1*  / complex






 

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