ENSMUSG00000024095


Mus musculus

Features
Gene ID: ENSMUSG00000024095
  
Biological name :Hnrnpll
  
Synonyms : Heteroous nuclear ribonucleoprotein L-like / Hnrnpll / Q921F4
  
Possible biological names infered from orthology : heterogeneous nuclear ribonucleoprotein L like / Q8WVV9
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E3
Gene start: 80029487
Gene end: 80062334
  
Corresponding Affymetrix probe sets: 10453082 (MoGene1.0st)   1425255_s_at (Mouse Genome 430 2.0 Array)   1427144_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058308
Ensembl peptide - ENSMUSP00000139075
Ensembl peptide - ENSMUSP00000139372
NCBI entrez gene - 72692     See in Manteia.
MGI - MGI:1919942
RefSeq - NM_144802
RefSeq Peptide - NP_659051
swissprot - Q921F4
swissprot - V9GXB6
Ensembl - ENSMUSG00000024095
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01100304.1ENSDARG00000116101Danio rerio
 HNRNPLLENSGALG00000008504Gallus gallus
 Q8WVV9ENSG00000143889Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hnrnpl / Q8R081 / Heteroous nuclear ribonucleoprotein L / P14866* / heterogeneous nuclear ribonucleoprotein L*ENSMUSG0000001516550
Ptbp1 / polypyrimidine tract binding protein 1 / P26599*ENSMUSG0000000649824
Ptbp3 / Q8BHD7 / Polypyrimidine tract-binding protein 3 / O95758*ENSMUSG0000002838223
Ptbp2 / Q91Z31 / Polypyrimidine tract-binding protein 2 / Q9UKA9*ENSMUSG0000002813423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006536  HnRNP-L/PTB
 IPR034983  hnRPLL, RNA recognition motif 3
 IPR034985  hnRPLL, RNA recognition motif 1
 IPR034986  hnRPLL, RNA recognition motif 2
 IPR034987  hnRPLL, RNA recognition motif 4
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0033120 positive regulation of RNA splicing ISO
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002145 abnormal T lymphocyte development "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Htr2ctm1Knk/Htr2ctm2Knk
Genetic Background: B6.Cg-Htr2ctm1Knk/Htr2ctm2Knk

 MP:0008051 abnormal memory T cell physiology "any functional anomaly of the set of long-lived T cells differentiated from T cells activated by a specific antigen encountered during a past immune response" [adiehl:Alex Diehl_MGI GO curator, Biology-Online.org:http://www.biology-online.org/, MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Htr2ctm1Knk/Htr2ctm2Knk
Genetic Background: B6.Cg-Htr2ctm1Knk/Htr2ctm2Knk

 MP:0008075 decreased CD4-positive T cell number "reduced number of the subset of T lymphocytes that carry the CD4 marker, recognize intravesicular peptides bound to MHC class-II molecules, and turn on antibody production" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Htr2ctm1Knk/Htr2ctm2Knk
Genetic Background: B6.Cg-Htr2ctm1Knk/Htr2ctm2Knk

 MP:0010833 abnormal memory T cell morphology "any structural anomaly of distinctly differentiated long-lived T cells that have the phenotype CD45RO-positive and CD127-positive" [CL:0000813, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, ISBN:0781735149]
Show

Allelic Composition: Htr2ctm1Knk/Htr2ctm2Knk
Genetic Background: B6.Cg-Htr2ctm1Knk/Htr2ctm2Knk

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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