ENSMUSG00000024664


Mus musculus

Features
Gene ID: ENSMUSG00000024664
  
Biological name :Fads3
  
Synonyms : Fads3 / Fatty acid desaturase 3 / Q9JJE7
  
Possible biological names infered from orthology : Q9Y5Q0
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 10041548
Gene end: 10059671
  
Corresponding Affymetrix probe sets: 10461423 (MoGene1.0st)   1418773_at (Mouse Genome 430 2.0 Array)   1435910_at (Mouse Genome 430 2.0 Array)   1449219_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000111659
NCBI entrez gene - 60527     See in Manteia.
MGI - MGI:1928740
RefSeq - NM_021890
RefSeq Peptide - NP_068690
swissprot - Q3T9H9
swissprot - Q9JJE7
Ensembl - ENSMUSG00000024664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fads2ENSDARG00000019532Danio rerio
 FADS3ENSG00000221968Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fads2 / Q9Z0R9 / Fatty acid desaturase 2 / O95864*ENSMUSG0000002466561
Q0VAX3 / 4833423E24Rik / Fatty acid desaturase 2-like protein FADS2P1 ENSMUSG0000007521752
Fads1 / Q920L1 / Fatty acid desaturase 1 / O60427*ENSMUSG0000001066352


Protein motifs (from Interpro)
Interpro ID Name
 IPR001199  Cytochrome b5-like heme/steroid binding domain
 IPR005804  Fatty acid desaturase domain
 IPR012171  Fatty acid desaturase
 IPR036400  Cytochrome b5-like heme/steroid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005281 increased fatty acid level "higher than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0005282 decreased fatty acid level "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0010359 increased liver free fatty acids level "elevated liver concentrations of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0010360 decreased liver free fatty acids level "reduced liver concentration of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tcf4em2Bdph/?
Genetic Background: involves: C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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