| MP:0000512 | intestinal ulcer | "lesions in the mucous lining of the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0000691 | enlarged spleen | "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0000706 | small thymus | "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0001125 | abnormal oocytes | "anomalous structure of immature ova" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0001129 | impaired ovarian folliculogenesis | "a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0001132 | absent mature ovarian follicles | "failure of ovarian follicle differentiation" [J:35782] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0001146 | abnormal testis morphology | "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001194 | dermatitis | "inflammation of the skin" [J:65146] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001209 | spontaneous skin ulceration | "unpredictable appearance of skin lesions, usually with inflammation" [J:65302] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Meox1tm1Bmk/Meox1tm1Bmk,Meox2tm1Vpa/Meox2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001919 | abnormal reproductive system physiology | "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
|
| MP:0001929 | abnormal gametogenesis | "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0002223 | lymphoid hypoplasia | "decreased cell number in lymphatic tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0002357 | abnormal spleen white pulp morphology | "anomalous structure or formation of the splenic area consisting of lymph nodules and diffuse lymphatic tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0002371 | abnormal thymus cortex morphology | "anomalous structure or development of the outer area of thymus lobules" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0002451 | abnormal macrophage physiology | "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0002551 | abnormal blood coagulation | "altered ability or inability of the blood to clot" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0002682 | reduced number of mature ovarian follicles | "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0002784 | abnormal Sertoli cell morphology | "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0003068 | enlarged kidney | "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0003356 | impaired lutenization | "atypical transformation of the mature ovarian follicle and its theca interna into a corpus luteum after ovulation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:57854, J:43075] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0003696 | abnormal zona pellucida | "anomaly or absence of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0003697 | absent zona pellucida | "missing the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0004884 | abnormal testicular physiology | "anomaly or loss either the production of male germ cells or the endocrine cells for the production testosterone" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0005159 | azoospermia | "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0005285 | decreased unsaturated fatty acid level | "less than normal non-circulating level of organic, monobasic acids derived from hydrocarbons in which the carbon chain has one or more double or triple carbon-carbon bonds " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0005464 | abnormal platelet physiology | "atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0005606 | increased bleeding time | "greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0006380 | abnormal spermatid morphology | "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0008279 | arrest of spermiogenesis | "block in the process by which a spermatid transforms into a functional spermatozoon" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0008476 | increased spleen red pulp amount | "increase in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0008868 | abnormal granulosa cell morphology | "any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0009355 | increased liver triglyceride level | "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0009368 | absent theca folliculi | "absence of the internal, external or both layers of the sheath of stroma surrounding a secondary ovarian follicle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0009549 | impaired platelet aggregation | "decrease in the ability of one platelet to one or more other platelets via adhesion molecules" [GO:0070527] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0009763 | increased sensitivity to induced morbidity/mortality | "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0009815 | decreased prostaglandin level | "reduction in the amount in the body of any of a class of mediators with effects of vasodilation, vasoconstriction, and smooth muscle stimulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Rom1Rgsc1156/Rom1+
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl
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| MP:0010180 | increased susceptibility to weight loss | "greater decrease in body weight over time when compared to the average decrease in weight in response to dietary modification, fasting or caloric restriction" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0011940 | decreased food intake | "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Fads2tm1Mtna/Fads2tm1Mtna
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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