ENSMUSG00000025280


Mus musculus

Features
Gene ID: ENSMUSG00000025280
  
Biological name :Polr3a
  
Synonyms : Polr3a / polymerase (RNA) III (DNA directed) polypeptide A
  
Possible biological names infered from orthology : O14802 / RNA polymerase III subunit A
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: A3
Gene start: 24448696
Gene end: 24487058
  
Corresponding Affymetrix probe sets: 10418131 (MoGene1.0st)   1434453_at (Mouse Genome 430 2.0 Array)   1437525_a_at (Mouse Genome 430 2.0 Array)   1444310_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153243
Ensembl peptide - ENSMUSP00000026322
NCBI entrez gene - 218832     See in Manteia.
MGI - MGI:2681836
RefSeq - NM_001081247
RefSeq - XM_006518819
RefSeq Peptide - NP_001074716
swissprot - B2RXC6
swissprot - Q7TSI4
Ensembl - ENSMUSG00000025280
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr3aENSDARG00000102569Danio rerio
 POLR3AENSGALG00000004947Gallus gallus
 O14802ENSG00000148606Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P08775 / Polr2a / DNA-directed RNA polymerase II subunit RPB1 ENSMUSG0000000519835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000722  RNA polymerase, alpha subunit
 IPR006592  RNA polymerase, N-terminal
 IPR007066  RNA polymerase Rpb1, domain 3
 IPR007080  RNA polymerase Rpb1, domain 1
 IPR007081  RNA polymerase Rpb1, domain 5
 IPR007083  RNA polymerase Rpb1, domain 4
 IPR035697  DNA-directed RNA polymerase III subunit RPC1, N-terminal
 IPR035698  DNA-directed RNA polymerase III subunit RPC1, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0032728 positive regulation of interferon-beta production ISO
 biological_processGO:0045087 innate immune response ISO
 biological_processGO:1903146 regulation of autophagy of mitochondrion ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex ISO
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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