ENSMUSG00000025366


Mus musculus

Features
Gene ID: ENSMUSG00000025366
  
Biological name :Esyt1
  
Synonyms : Esyt1 / Extended synaptotagmin-1 / Q3U7R1
  
Possible biological names infered from orthology : Q9BSJ8
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 128509965
Gene end: 128525871
  
Corresponding Affymetrix probe sets: 10373407 (MoGene1.0st)   1446311_at (Mouse Genome 430 2.0 Array)   1451099_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151519
Ensembl peptide - ENSMUSP00000026427
NCBI entrez gene - 23943     See in Manteia.
MGI - MGI:1344426
RefSeq - NM_011843
RefSeq Peptide - NP_035973
swissprot - A0A1W2P784
swissprot - Q3U7R1
Ensembl - ENSMUSG00000025366
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esyt1aENSDARG00000034714Danio rerio
 esyt1bENSDARG00000014239Danio rerio
 ESYT1ENSG00000139641Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Esyt2 / Q3TZZ7 / Extended synaptotagmin-2 / A0FGR8*ENSMUSG0000002117135
Esyt3 / Q5DTI8 / Extended synaptotagmin-3 / A0FGR9*ENSMUSG0000003768130
Mctp2 / Q5RJH2 / Multiple C2 and transmembrane domain-containing protein 2 / Q6DN12* / multiple C2 and transmembrane domain containing 2*ENSMUSG0000003277612
Mctp1 / E9PV86 / Multiple C2 and transmembrane domain-containing protein 1 / Q6DN14* / multiple C2 and transmembrane domain containing 1*ENSMUSG0000002159611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR031468  Synaptotagmin-like mitochondrial-lipid-binding domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0061817 endoplasmic reticulum-plasma membrane tethering IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0031227 intrinsic component of endoplasmic reticulum membrane IBA
 cellular_componentGO:0044232 organelle membrane contact site IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pitpnavb/Pitpnavb
Genetic Background: involves: C57BL/6J * DBA/2J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037681 Esyt3 / Q5DTI8 / Extended synaptotagmin-3 / A0FGR9*  / complex
 ENSMUSG00000021171 Esyt2 / Q3TZZ7 / Extended synaptotagmin-2 / A0FGR8*  / complex






 

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