ENSG00000139641


Homo sapiens

Features
Gene ID: ENSG00000139641
  
Biological name :ESYT1
  
Synonyms : ESYT1 / extended synaptotagmin 1 / Q9BSJ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.2
Gene start: 56118250
Gene end: 56144671
  
Corresponding Affymetrix probe sets: 208858_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267113
Ensembl peptide - ENSP00000447756
Ensembl peptide - ENSP00000377612
NCBI entrez gene - 23344     See in Manteia.
OMIM - 616670
RefSeq - NM_015292
RefSeq - NM_001184796
RefSeq Peptide - NP_001171725
RefSeq Peptide - NP_056107
swissprot - Q9BSJ8
swissprot - A0A024RB16
swissprot - F8VZB1
swissprot - A0A024RB17
Ensembl - ENSG00000139641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esyt1aENSDARG00000034714Danio rerio
 esyt1bENSDARG00000014239Danio rerio
 Esyt1ENSMUSG00000025366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ESYT2 / A0FGR8 / extended synaptotagmin 2ENSG0000011786835
ESYT3 / A0FGR9 / extended synaptotagmin 3ENSG0000015822030
MCTP1 / Q6DN14 / multiple C2 and transmembrane domain containing 1ENSG0000017547113
MCTP2 / Q6DN12 / multiple C2 and transmembrane domain containing 2ENSG0000014056312


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR031468  Synaptotagmin-like mitochondrial-lipid-binding domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0061817 endoplasmic reticulum-plasma membrane tethering IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0044232 organelle membrane contact site IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117868 ESYT2 / A0FGR8 / extended synaptotagmin 2  / complex
 ENSG00000158220 ESYT3 / A0FGR9 / extended synaptotagmin 3  / complex






 

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