ENSG00000158220


Homo sapiens

Features
Gene ID: ENSG00000158220
  
Biological name :ESYT3
  
Synonyms : A0FGR9 / ESYT3 / extended synaptotagmin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.3
Gene start: 138434586
Gene end: 138481686
  
Corresponding Affymetrix probe sets: 1554912_at (Human Genome U133 Plus 2.0 Array)   1557793_at (Human Genome U133 Plus 2.0 Array)   239770_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417388
Ensembl peptide - ENSP00000289135
Ensembl peptide - ENSP00000374218
NCBI entrez gene - 83850     See in Manteia.
OMIM - 616692
RefSeq - XM_017007307
RefSeq - NM_001322831
RefSeq - NM_001322834
RefSeq - NM_031913
RefSeq Peptide - NP_001309760
RefSeq Peptide - NP_001309763
RefSeq Peptide - NP_114119
swissprot - A0FGR9
swissprot - H7BXJ6
Ensembl - ENSG00000158220
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esyt3ENSDARG00000006422Danio rerio
 ESYT3ENSGALG00000012092Gallus gallus
 Esyt3ENSMUSG00000037681Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ESYT2 / A0FGR8 / extended synaptotagmin 2ENSG0000011786840
ESYT1 / Q9BSJ8 / extended synaptotagmin 1ENSG0000013964138
MCTP1 / Q6DN14 / multiple C2 and transmembrane domain containing 1ENSG0000017547115
MCTP2 / Q6DN12 / multiple C2 and transmembrane domain containing 2ENSG0000014056313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR031468  Synaptotagmin-like mitochondrial-lipid-binding domain
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0061817 endoplasmic reticulum-plasma membrane tethering IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031227 intrinsic component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0044232 organelle membrane contact site IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000117868 ESYT2 / A0FGR8 / extended synaptotagmin 2  / complex
 ENSG00000139641 ESYT1 / Q9BSJ8 / extended synaptotagmin 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr