ENSMUSG00000025903


Mus musculus

Features
Gene ID: ENSMUSG00000025903
  
Biological name :Lypla1
  
Synonyms : Acyl-protein thioesterase 1 / Lypla1 / P97823
  
Possible biological names infered from orthology : lysophospholipase I / O75608
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: A1
Gene start: 4807788
Gene end: 4848410
  
Corresponding Affymetrix probe sets: 10344624 (MoGene1.0st)   1431607_at (Mouse Genome 430 2.0 Array)   1448244_at (Mouse Genome 430 2.0 Array)   1453949_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119456
Ensembl peptide - ENSMUSP00000137647
Ensembl peptide - ENSMUSP00000137248
Ensembl peptide - ENSMUSP00000137104
Ensembl peptide - ENSMUSP00000027036
Ensembl peptide - ENSMUSP00000111191
Ensembl peptide - ENSMUSP00000118453
NCBI entrez gene - 18777     See in Manteia.
MGI - MGI:1344588
RefSeq - XM_006495472
RefSeq - NM_008866
RefSeq - XM_006495471
RefSeq Peptide - NP_032892
RefSeq Peptide - NP_001342641
swissprot - D3Z269
swissprot - P97823
swissprot - D3YUG4
swissprot - J3QQ63
swissprot - J3QP56
swissprot - D3Z111
Ensembl - ENSMUSG00000025903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lypla1ENSDARG00000104228Danio rerio
 LYPLA1ENSGALG00000040421Gallus gallus
 LYPLA1ENSG00000120992Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lypla2 / Q9WTL7 / Acyl-protein thioesterase 2 / O95372* / lysophospholipase II*ENSMUSG0000002867063
Lyplal1 / lysophospholipase like 1 / Q5VWZ2*ENSMUSG0000003924630


Protein motifs (from Interpro)
Interpro ID Name
 IPR003140  Phospholipase/carboxylesterase/thioesterase
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002084 protein depalmitoylation IMP
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0042997 negative regulation of Golgi to plasma membrane protein transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0008474 palmitoyl-(protein) hydrolase activity IBA
 molecular_functionGO:0016298 lipase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IBA


Pathways (from Reactome)
Pathway description
eNOS activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028978 Nos3 / P70313 / Nitric oxide synthase, endothelial / P29474* / nitric oxide synthase 3*  / reaction
 ENSMUSG00000025903 Lypla1 / P97823 / Acyl-protein thioesterase 1 / O75608* / lysophospholipase I*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr