ENSMUSG00000026080


Mus musculus

Features
Gene ID: ENSMUSG00000026080
  
Biological name :Chst10
  
Synonyms : carbohydrate sulfotransferase 10 / Chst10
  
Possible biological names infered from orthology : O43529
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: B
Gene start: 38863867
Gene end: 38898161
  
Corresponding Affymetrix probe sets: 10354157 (MoGene1.0st)   1426620_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027249
Ensembl peptide - ENSMUSP00000142028
Ensembl peptide - ENSMUSP00000141604
Ensembl peptide - ENSMUSP00000141481
Ensembl peptide - ENSMUSP00000141470
Ensembl peptide - ENSMUSP00000141295
NCBI entrez gene - 98388     See in Manteia.
MGI - MGI:2138283
RefSeq - NM_145142
RefSeq - XM_006496364
RefSeq - XM_006496365
RefSeq Peptide - NP_660124
swissprot - A2RSS2
swissprot - A0A0A6YVW5
swissprot - A0A0A6YXK3
swissprot - A0A0A6YWM2
swissprot - A0A0A6YWB7
swissprot - A0A0A6YWA7
Ensembl - ENSMUSG00000026080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chst10ENSDARG00000031632Danio rerio
 CHST10ENSGALG00000016769Gallus gallus
 CHST10ENSG00000115526Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chst8 / Q8BQ86 / Carbohydrate sulfotransferase 8 / Q9H2A9*ENSMUSG0000006040228
Chst9 / Q76EC5 / Carbohydrate sulfotransferase 9 / Q7L1S5*ENSMUSG0000004716128
Chst12 / Q99LL3 / Carbohydrate sulfotransferase 12 / Q9NRB3*ENSMUSG0000003659927
Chst11 / Q9JME2 / Carbohydrate sulfotransferase 11 / Q9NPF2*ENSMUSG0000003461226
Chst13 / carbohydrate (chondroitin 4) sulfotransferase 13 / Q8NET6* / carbohydrate sulfotransferase 13*ENSMUSG0000005664325
Chst14 / Q80V53 / Carbohydrate sulfotransferase 14 / Q8NCH0*ENSMUSG0000007491622


Protein motifs (from Interpro)
Interpro ID Name
 IPR005331  Sulfotransferase
 IPR018011  Carbohydrate sulfotransferase 8-10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0016051 carbohydrate biosynthetic process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Reactions specific to the complex N-glycan synthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001473 reduced long term potentiation "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0002063 abnormal learning/memory/conditioning "altered ability to receive, store or recall informational stimuli" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002206 abnormal CNS synaptic transmission "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003370 increased circulating estrogen level "greater than normal blood concentration of any substance that causes development of the female reproductive organs and secondary sexual characteristics" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0004904 increased uterus weight "increase in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0004906 enlarged uterus 
Show

Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

 MP:0009092 endometrium hyperplasia "overdevelopment or increased size, usually due an increased number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kcnmb1tm1Ltor/Kcnmb1tm1Ltor
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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