ENSMUSG00000026202


Mus musculus

Features
Gene ID: ENSMUSG00000026202
  
Biological name :Tuba4a
  
Synonyms : P68368 / Tuba4a / tubulin, alpha 4A
  
Possible biological names infered from orthology : P68366
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C4
Gene start: 75214228
Gene end: 75219865
  
Corresponding Affymetrix probe sets: 10355806 (MoGene1.0st)   1417373_a_at (Mouse Genome 430 2.0 Array)   1417374_at (Mouse Genome 430 2.0 Array)   1417375_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078429
Ensembl peptide - ENSMUSP00000141097
Ensembl peptide - ENSMUSP00000140970
Ensembl peptide - ENSMUSP00000140881
Ensembl peptide - ENSMUSP00000140657
Ensembl peptide - ENSMUSP00000140552
Ensembl peptide - ENSMUSP00000140321
NCBI entrez gene - 22145     See in Manteia.
MGI - MGI:1095410
RefSeq - XM_006496478
RefSeq - NM_001313723
RefSeq - NM_001313724
RefSeq - NM_009447
RefSeq Peptide - NP_033473
RefSeq Peptide - NP_001300652
RefSeq Peptide - NP_001300653
swissprot - A0A0A0MQA5
swissprot - A0A087WSB0
swissprot - A0A087WS35
swissprot - A0A087WQS4
swissprot - A0A087WRB4
swissprot - A0A087WSL5
swissprot - P68368
Ensembl - ENSMUSG00000026202
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tuba8l2ENSDARG00000031164Danio rerio
 ENSGALG00000011324Gallus gallus
 ENSGALG00000000433Gallus gallus
 P68366ENSG00000127824Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P05213 / Tuba1b / tubulin, alpha 1B / P68363*ENSMUSG0000002300497
P68369 / Tuba1a / tubulin, alpha 1A / Q71U36*ENSMUSG0000007223596
P68373 / Tuba1c / tubulin, alpha 1CENSMUSG0000004309196
P05214 / Tuba3a / tubulin, alpha 3A / Q13748* / TUBA3C* / tubulin alpha 3c*ENSMUSG0000006770295
Tuba3b / P05214 / tubulin, alpha 3B / TUBA3D* / Q13748* / Q6PEY2* / TUBA3E* / tubulin alpha 3d* / tubulin alpha 3e*ENSMUSG0000006733895
AC161165.4 / Q9BQE3* / TUBA1C* / tubulin alpha 1c*ENSMUSG0000011635858


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002452  Alpha tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007017 microtubule-based process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton ISO
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Hedgehog off state
Cilium Assembly
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
Hedgehog on state
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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