ENSMUSG00000023004


Mus musculus

Features
Gene ID: ENSMUSG00000023004
  
Biological name :Tuba1b
  
Synonyms : P05213 / Tuba1b / tubulin, alpha 1B
  
Possible biological names infered from orthology : P68363
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 98931425
Gene end: 98934565
  
Corresponding Affymetrix probe sets: 10426650 (MoGene1.0st)   10432398 (MoGene1.0st)   10587780 (MoGene1.0st)   10592058 (MoGene1.0st)   1423846_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076777
NCBI entrez gene - 22143     See in Manteia.
MGI - MGI:107804
RefSeq - NM_011654
RefSeq - XM_006520756
RefSeq Peptide - NP_035784
swissprot - P05213
Ensembl - ENSMUSG00000023004
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tuba2ENSDARG00000045014Danio rerio
 P68363ENSG00000123416Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P68369 / Tuba1a / tubulin, alpha 1A / Q71U36*ENSMUSG00000072235100
P68373 / Tuba1c / tubulin, alpha 1CENSMUSG0000004309198
P05214 / Tuba3a / tubulin, alpha 3A / Q13748* / TUBA3C* / tubulin alpha 3c*ENSMUSG0000006770297
Tuba3b / P05214 / tubulin, alpha 3B / TUBA3D* / Q13748* / Q6PEY2* / TUBA3E* / tubulin alpha 3d* / tubulin alpha 3e*ENSMUSG0000006733897
P68368 / Tuba4a / tubulin, alpha 4A / P68366*ENSMUSG0000002620296
AC161165.4 / Q9BQE3* / TUBA1C* / tubulin alpha 1c*ENSMUSG0000011635859


Protein motifs (from Interpro)
Interpro ID Name
 IPR000217  Tubulin
 IPR002452  Alpha tubulin
 IPR003008  Tubulin/FtsZ, GTPase domain
 IPR008280  Tubulin/FtsZ, C-terminal
 IPR017975  Tubulin, conserved site
 IPR018316  Tubulin/FtsZ, 2-layer sandwich domain
 IPR036525  Tubulin/FtsZ, GTPase domain superfamily
 IPR037103  Tubulin/FtsZ, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IDA
 biological_processGO:0007017 microtubule-based process IEA
 biological_processGO:0071353 cellular response to interleukin-4 IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Recruitment of NuMA to mitotic centrosomes
Recycling pathway of L1
Hedgehog off state
Cilium Assembly
Intraflagellar transport
RHO GTPases activate IQGAPs
Hedgehog on state
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
Carboxyterminal post-translational modifications of tubulin
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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