ENSMUSG00000026439


Mus musculus

Features
Gene ID: ENSMUSG00000026439
  
Biological name :Rbbp5
  
Synonyms : Mus musculus retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit (Rbbp5), transcript variant 3, mRNA. / Q8BX09 / Rbbp5
  
Possible biological names infered from orthology : Q15291 / RB binding protein 5, histone lysine methyltransferase complex subunit
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 132477365
Gene end: 132505659
  
Corresponding Affymetrix probe sets: 10349809 (MoGene1.0st)   1428886_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139519
Ensembl peptide - ENSMUSP00000141176
Ensembl peptide - ENSMUSP00000141003
Ensembl peptide - ENSMUSP00000140790
Ensembl peptide - ENSMUSP00000140344
Ensembl peptide - ENSMUSP00000027700
NCBI entrez gene - 213464     See in Manteia.
MGI - MGI:1918367
RefSeq - XM_006529359
RefSeq - NM_001357487
RefSeq - NM_172517
RefSeq - XM_006529357
RefSeq - XM_006529358
RefSeq Peptide - NP_001344416
RefSeq Peptide - NP_766105
swissprot - A0A087WQU2
swissprot - A0A087WST2
swissprot - Q8BX09
swissprot - A0A087WRV7
swissprot - A0A0R4J2B6
Ensembl - ENSMUSG00000026439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rbbp5ENSDARG00000042147Danio rerio
 RBBP5ENSGALG00000000668Gallus gallus
 RBBP5ENSG00000117222Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0043627 response to estrogen ISO
 biological_processGO:0051568 histone H3-K4 methylation ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0035097 histone methyltransferase complex ISO
 cellular_componentGO:0044666 MLL3/4 complex ISO
 cellular_componentGO:0048188 Set1C/COMPASS complex IEA
 cellular_componentGO:0071339 MLL1 complex ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0035064 methylated histone binding ISO
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO


Pathways (from Reactome)
Pathway description
Formation of the beta-catenin:TCF transactivating complex
PKMTs methylate histone lysines
Deactivation of the beta-catenin transactivating complex
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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