ENSMUSG00000026547


Mus musculus

Features
Gene ID: ENSMUSG00000026547
  
Biological name :Tagln2
  
Synonyms : Q9WVA4 / Tagln2 / Transgelin-2
  
Possible biological names infered from orthology : P37802
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H3
Gene start: 172500047
Gene end: 172507380
  
Corresponding Affymetrix probe sets: 10351825 (MoGene1.0st)   1420245_x_at (Mouse Genome 430 2.0 Array)   1426529_a_at (Mouse Genome 430 2.0 Array)   1439407_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000106861
Ensembl peptide - ENSMUSP00000141983
Ensembl peptide - ENSMUSP00000106859
NCBI entrez gene - 21346     See in Manteia.
MGI - MGI:1312985
RefSeq - NM_178598
RefSeq Peptide - NP_848713
swissprot - A0A0A6YXG6
swissprot - Q9WVA4
Ensembl - ENSMUSG00000026547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAGLN2ENSGALG00000036086Gallus gallus
 P37802ENSG00000158710Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9R1Q8 / Tagln3 / Transgelin-3 / Q9UI15*ENSMUSG0000002265872
Tagln / P37804 / Transgelin / Q01995*ENSMUSG0000003208568
Cnn3 / Q9DAW9 / Calponin-3 / Q15417*ENSMUSG0000005393144
Cnn2 / Q08093 / Calponin-2 / Q99439*ENSMUSG0000000466543
Cnn1 / Q08091 / Calponin-1 / P51911*ENSMUSG0000000134942


Protein motifs (from Interpro)
Interpro ID Name
 IPR000557  Calponin repeat
 IPR001061  Transgelin-2
 IPR001715  Calponin homology domain
 IPR003096  Smooth muscle protein/calponin
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030855 epithelial cell differentiation ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001828 abnormal T cell activation "anomaly in the process of producing effector T cells from naive T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: H2-D1em5Dvs/H2-D1em5Dvs,H2-K1em1Dvs/H2-K1em1Dvs,Tg(HLA-A/H2-D/B2M)1Dvs/?
Genetic Background: NOD/ShiLtDvs-H2-K1em1Dvs H2-D1em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs

Allelic Composition: Tagln2tm1Cdj/Tagln2tm1Cdj,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: H2-D1em5Dvs/H2-D1em5Dvs,H2-K1em1Dvs/H2-K1em1Dvs,Tg(HLA-A/H2-D/B2M)1Dvs/?
Genetic Background: NOD/ShiLtDvs-H2-K1em1Dvs H2-D1em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs

 MP:0005078 abnormal cytotoxic T cell physiology "impaired function of the subset of CD8+ T lymphocytes capable of directly killing appropriately targeted cells " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: H2-D1em5Dvs/H2-D1em5Dvs,H2-K1em1Dvs/H2-K1em1Dvs,Tg(HLA-A/H2-D/B2M)1Dvs/?
Genetic Background: NOD/ShiLtDvs-H2-K1em1Dvs H2-D1em5Dvs Tg(HLA-A/H2-D/B2M)1Dvs/Dvs

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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