ENSMUSG00000027221


Mus musculus

Features
Gene ID: ENSMUSG00000027221
  
Biological name :Chst1
  
Synonyms : Carbohydrate sulfotransferase 1 / Chst1 / Q9EQC0
  
Possible biological names infered from orthology : O43916
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E1
Gene start: 92599707
Gene end: 92615250
  
Corresponding Affymetrix probe sets: 10474045 (MoGene1.0st)   1449147_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000064246
NCBI entrez gene - 76969     See in Manteia.
MGI - MGI:1924219
RefSeq - XM_006500389
RefSeq - NM_023850
RefSeq - XM_006500388
RefSeq Peptide - NP_076339
RefSeq Peptide - NP_001343481
RefSeq Peptide - NP_001343482
swissprot - Q3UY35
swissprot - Q9EQC0
Ensembl - ENSMUSG00000027221
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chst1ENSDARG00000088593Danio rerio
 CHST1ENSGALG00000008440Gallus gallus
 CHST1ENSG00000175264Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chst3 / O88199 / Carbohydrate sulfotransferase 3 / Q7LGC8*ENSMUSG0000005733742
Chst7 / Q9EP78 / Carbohydrate sulfotransferase 7 / Q9NS84*ENSMUSG0000003734730
Chst5 / Q9QUP4 / Carbohydrate sulfotransferase 5 / CHST6* / Q9GZS9* / Q9GZX3* / carbohydrate sulfotransferase 6*ENSMUSG0000003195230
Chst2 / Q80WV3 / Carbohydrate sulfotransferase 2 / Q9Y4C5*ENSMUSG0000003335029
Chst4 / carbohydrate sulfotransferase 4 / Q8NCG5*ENSMUSG0000003593029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR016469  Carbohydrate sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006012 galactose metabolic process IEA
 biological_processGO:0006790 sulfur compound metabolic process IBA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0042339 keratan sulfate metabolic process ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity IBA
 molecular_functionGO:0008146 sulfotransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0045130 keratan sulfotransferase activity ISO


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001353 increased aggression to other mice "when compared to controls, subjects exhibit greater than the normal level of domineering, assaultive posture and/or hostile physical action toward other mice" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Webster s II New College Dictionary:ISBN 0-395-70869-9]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003156 abnormal lymphocyte migration/homing "altered ability of blood lymphocytes to bind to high endothelial venules (HEV), tether and roll along the luminal aspects of HEV, and migrate into the lymph nodes" [acv:Alicia C. Valenzuela, Mouse Genome Informatics Curator, J:92231]
Show

Allelic Composition: Chst1tm1(KOMP)Vlcg/Chst1tm1(KOMP)Vlcg,Chst2tm1Tmu/Chst2tm1Tmu,Chst4tm1Sdr/Chst4tm1Sdr
Genetic Background: involves: 129S2/SvPas * C57BL/6NTac

 MP:0005015 increased T cell number "greater than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bub1btm1.1Hsl/Bub1b+,Tg(HIST1H2BB/EGFP)1Pa/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr