ENSMUSG00000027433


Mus musculus

Features
Gene ID: ENSMUSG00000027433
  
Biological name :Xrn2
  
Synonyms : 5-3 exoribonuclease 2 / Q9DBR1 / Xrn2
  
Possible biological names infered from orthology : Q9H0D6
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: G2
Gene start: 147012996
Gene end: 147078000
  
Corresponding Affymetrix probe sets: 10476834 (MoGene1.0st)   1422842_at (Mouse Genome 430 2.0 Array)   1422843_at (Mouse Genome 430 2.0 Array)   1450777_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028921
NCBI entrez gene - 24128     See in Manteia.
MGI - MGI:894687
RefSeq - XM_011239519
RefSeq - NM_011917
RefSeq - XM_006499450
RefSeq - XM_006499451
RefSeq Peptide - NP_036047
swissprot - Q9DBR1
Ensembl - ENSMUSG00000027433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xrn2ENSDARG00000101900Danio rerio
 XRN2ENSGALG00000008372Gallus gallus
 XRN2ENSG00000088930Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004859  Putative 5-3 exonuclease
 IPR017151  5"-3" exoribonuclease type 2
 IPR027073  5"-3" exoribonuclease


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000738 DNA catabolic process, exonucleolytic IEA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006281 DNA repair NAS
 biological_processGO:0006310 DNA recombination NAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006353 DNA-templated transcription, termination IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007017 microtubule-based process TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016070 RNA metabolic process IGI
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0016235 aggresome IEA
 molecular_functionGO:0000175 3"-5"-exoribonuclease activity ISO
 molecular_functionGO:0001147 transcription termination site sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004534 5"-3" exoribonuclease activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008409 5"-3" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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