ENSMUSG00000027890


Mus musculus

Features
Gene ID: ENSMUSG00000027890
  
Biological name :Gstm4
  
Synonyms : glutathione S-transferase mu 4 / Gstm4
  
Possible biological names infered from orthology : Q03013
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.3
Gene start: 108040408
Gene end: 108044894
  
Corresponding Affymetrix probe sets: 10501235 (MoGene1.0st)   1424835_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029489
Ensembl peptide - ENSMUSP00000102281
Ensembl peptide - ENSMUSP00000136643
NCBI entrez gene - 14865     See in Manteia.
MGI - MGI:95862
RefSeq - XM_006501021
RefSeq - NM_001160411
RefSeq - NM_026764
RefSeq - XM_006501018
RefSeq - XM_006501020
RefSeq Peptide - NP_001153883
RefSeq Peptide - NP_081040
swissprot - Q8R5I6
swissprot - A2AE91
Ensembl - ENSMUSG00000027890
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gstm.1ENSDARG00000042533Danio rerio
 gstm.2ENSDARG00000029473Danio rerio
 gstm.3ENSDARG00000088116Danio rerio
 GSTM2ENSGALG00000032922Gallus gallus
 GSTM4ENSG00000168765Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gstm7 / Q80W21 / Glutathione S-transferase Mu 7 / GSTM2* / P28161* / glutathione S-transferase mu 2*ENSMUSG0000000403579
Gstm2 / P15626 / Glutathione S-transferase Mu 2 / GSTM5* / GSTM1* / P09488* / P46439* / glutathione S-transferase mu 1* / glutathione S-transferase mu 5*ENSMUSG0000004056279
Gstm6 / O35660 / Glutathione S-transferase Mu 6 / GSTM5* / GSTM1* / P09488* / P46439* / glutathione S-transferase mu 5* / glutathione S-transferase mu 1*ENSMUSG0000006876275
Gstm3 / P19639 / Glutathione S-transferase Mu 3 ENSMUSG0000000403874
Gstm1 / P10649 / Glutathione S-transferase Mu 1 ENSMUSG0000005813572
Gstm5 / P48774 / Glutathione S-transferase Mu 5 / GSTM3* / P21266* / glutathione S-transferase mu 3*ENSMUSG0000000403269
Gm6665 / GSTM1* / GSTM5* / P46439* / P09488* / glutathione S-transferase mu 1* / glutathione S-transferase mu 5*ENSMUSG0000009156131
Gstp1 / P19157 / Glutathione S-transferase P 1 / P09211* / glutathione S-transferase pi 1*ENSMUSG0000006080329
Gstp2 / P46425 / Glutathione S-transferase P 2 / GSTP1* / P09211* / glutathione S-transferase pi 1*ENSMUSG0000003815529
Gstp3ENSMUSG0000005821627


Protein motifs (from Interpro)
Interpro ID Name
 IPR003081  Glutathione S-transferase, Mu class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0018916 nitrobenzene metabolic process IDA
 biological_processGO:0042178 xenobiotic catabolic process ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0045171 intercellular bridge ISO
 molecular_functionGO:0004364 glutathione transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043295 glutathione binding ISO


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Biosynthesis of maresin conjugates in tissue regeneration (MCTR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Grin2btm1e.1(KOMP)Wtsi/Grin2b+
Genetic Background: C57BL/6N-Grin2btm1e.1(KOMP)Wtsi/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027890 Gstm4 / glutathione S-transferase mu 4 / Q03013*  / complex






 

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