ENSG00000168765


Homo sapiens

Features
Gene ID: ENSG00000168765
  
Biological name :GSTM4
  
Synonyms : glutathione S-transferase mu 4 / GSTM4 / Q03013
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.3
Gene start: 109656081
Gene end: 109674836
  
Corresponding Affymetrix probe sets: 204149_s_at (Human Genome U133 Plus 2.0 Array)   204418_x_at (Human Genome U133 Plus 2.0 Array)   204550_x_at (Human Genome U133 Plus 2.0 Array)   210912_x_at (Human Genome U133 Plus 2.0 Array)   215333_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000316471
Ensembl peptide - ENSP00000491134
Ensembl peptide - ENSP00000358851
Ensembl peptide - ENSP00000358848
Ensembl peptide - ENSP00000336744
NCBI entrez gene - 2948     See in Manteia.
OMIM - 138333
RefSeq - XM_017001085
RefSeq - XM_017001088
RefSeq - XM_017001087
RefSeq - XM_017001086
RefSeq - NM_000850
RefSeq - NM_147148
RefSeq Peptide - NP_000841
RefSeq Peptide - NP_671489
swissprot - Q03013
swissprot - A6NNT0
swissprot - A0A0A0MR85
swissprot - A0A140VKE3
swissprot - A0A1W2PNX1
Ensembl - ENSG00000168765
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gstm.1ENSDARG00000042533Danio rerio
 gstm.2ENSDARG00000029473Danio rerio
 gstm.3ENSDARG00000088116Danio rerio
 GSTM2ENSGALG00000032922Gallus gallus
 Gstm4ENSMUSG00000027890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTM1 / P09488 / glutathione S-transferase mu 1ENSG0000013418487
GSTM2 / P28161 / glutathione S-transferase mu 2ENSG0000021336683
GSTM5 / P46439 / glutathione S-transferase mu 5ENSG0000013420183
GSTM3 / P21266 / glutathione S-transferase mu 3ENSG0000013420272
GSTP1 / P09211 / glutathione S-transferase pi 1ENSG0000008420727


Protein motifs (from Interpro)
Interpro ID Name
 IPR003081  Glutathione S-transferase, Mu class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0018916 nitrobenzene metabolic process IEA
 biological_processGO:0042178 xenobiotic catabolic process IDA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043295 glutathione binding IDA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Biosynthesis of maresin conjugates in tissue regeneration (MCTR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168765 GSTM4 / Q03013 / glutathione S-transferase mu 4  / complex






 

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