ENSG00000134184


Homo sapiens

Features
Gene ID: ENSG00000134184
  
Biological name :GSTM1
  
Synonyms : glutathione S-transferase mu 1 / GSTM1 / P09488
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.3
Gene start: 109687814
Gene end: 109709039
  
Corresponding Affymetrix probe sets: 204418_x_at (Human Genome U133 Plus 2.0 Array)   204550_x_at (Human Genome U133 Plus 2.0 Array)   215333_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358838
Ensembl peptide - ENSP00000358834
Ensembl peptide - ENSP00000455929
Ensembl peptide - ENSP00000456315
Ensembl peptide - ENSP00000234981
Ensembl peptide - ENSP00000311469
NCBI entrez gene - 2944     See in Manteia.
OMIM - 138350
RefSeq - XM_005270782
RefSeq - NM_000561
RefSeq - NM_146421
RefSeq Peptide - NP_000552
RefSeq Peptide - NP_666533
swissprot - B9ZVX7
swissprot - P09488
swissprot - X5D932
swissprot - E7EWW9
swissprot - H3BRM6
swissprot - H3BQT3
swissprot - X5DR03
Ensembl - ENSG00000134184
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gstm.1ENSDARG00000042533Danio rerio
 gstm.2ENSDARG00000029473Danio rerio
 gstm.3ENSDARG00000088116Danio rerio
 GSTM2ENSGALG00000032922Gallus gallus
 Gm6665ENSMUSG00000091561Mus musculus
 Gstm2ENSMUSG00000040562Mus musculus
 Gstm6ENSMUSG00000068762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTM5 / P46439 / glutathione S-transferase mu 5ENSG0000013420188
GSTM4 / Q03013 / glutathione S-transferase mu 4ENSG0000016876587
GSTM2 / P28161 / glutathione S-transferase mu 2ENSG0000021336684
GSTM3 / P21266 / glutathione S-transferase mu 3ENSG0000013420272
GSTP1 / P09211 / glutathione S-transferase pi 1ENSG0000008420727


Protein motifs (from Interpro)
Interpro ID Name
 IPR003081  Glutathione S-transferase, Mu class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0018916 nitrobenzene metabolic process IDA
 biological_processGO:0042178 xenobiotic catabolic process IDA
 biological_processGO:0070458 cellular detoxification of nitrogen compound IDA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0043295 glutathione binding IDA


Pathways (from Reactome)
Pathway description
Glutathione conjugation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134184 GSTM1 / P09488 / glutathione S-transferase mu 1  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr