ENSG00000134202


Homo sapiens

Features
Gene ID: ENSG00000134202
  
Biological name :GSTM3
  
Synonyms : glutathione S-transferase mu 3 / GSTM3 / P21266
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.3
Gene start: 109733932
Gene end: 109741038
  
Corresponding Affymetrix probe sets: 202554_s_at (Human Genome U133 Plus 2.0 Array)   235867_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354357
Ensembl peptide - ENSP00000444978
Ensembl peptide - ENSP00000256594
NCBI entrez gene - 2947     See in Manteia.
OMIM - 138390
RefSeq - NM_000849
RefSeq Peptide - NP_000840
swissprot - A0A0A0MTN3
swissprot - P21266
swissprot - Q6FGJ9
Ensembl - ENSG00000134202
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gstm.1ENSDARG00000042533Danio rerio
 gstm.2ENSDARG00000029473Danio rerio
 gstm.3ENSDARG00000088116Danio rerio
 GSTM2ENSGALG00000032922Gallus gallus
 Gstm5ENSMUSG00000004032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GSTM1 / P09488 / glutathione S-transferase mu 1ENSG0000013418470
GSTM4 / Q03013 / glutathione S-transferase mu 4ENSG0000016876570
GSTM5 / P46439 / glutathione S-transferase mu 5ENSG0000013420169
GSTM2 / P28161 / glutathione S-transferase mu 2ENSG0000021336666
GSTP1 / P09211 / glutathione S-transferase pi 1ENSG0000008420730


Protein motifs (from Interpro)
Interpro ID Name
 IPR003081  Glutathione S-transferase, Mu class
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IDA
 biological_processGO:0008065 establishment of blood-nerve barrier TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0018916 nitrobenzene metabolic process IDA
 biological_processGO:0042178 xenobiotic catabolic process IDA
 biological_processGO:0043627 response to estrogen IEP
 biological_processGO:0070458 cellular detoxification of nitrogen compound IDA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0035686 sperm fibrous sheath IEA
 cellular_componentGO:0045171 intercellular bridge IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043295 glutathione binding IDA


Pathways (from Reactome)
Pathway description
Glutathione conjugation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134202 GSTM3 / P21266 / glutathione S-transferase mu 3  / complex






 

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