ENSMUSG00000027940


Mus musculus

Features
Gene ID: ENSMUSG00000027940
  
Biological name :Tpm3
  
Synonyms : P21107 / Tpm3 / tropomyosin 3, gamma
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 90072649
Gene end: 90100902
  
Corresponding Affymetrix probe sets: 10416940 (MoGene1.0st)   10493633 (MoGene1.0st)   1427260_a_at (Mouse Genome 430 2.0 Array)   1427567_a_at (Mouse Genome 430 2.0 Array)   1436958_x_at (Mouse Genome 430 2.0 Array)   1449996_a_at (Mouse Genome 430 2.0 Array)   1449997_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113056
Ensembl peptide - ENSMUSP00000029549
Ensembl peptide - ENSMUSP00000113219
Ensembl peptide - ENSMUSP00000115565
Ensembl peptide - ENSMUSP00000114229
Ensembl peptide - ENSMUSP00000113978
Ensembl peptide - ENSMUSP00000113578
NCBI entrez gene - 59069     See in Manteia.
MGI - MGI:1890149
RefSeq - XM_017319678
RefSeq - NM_001253738
RefSeq - NM_001253740
RefSeq - NM_001271764
RefSeq - NM_001293748
RefSeq - NM_001293749
RefSeq - NM_001357581
RefSeq - NM_022314
RefSeq - XM_006501835
RefSeq - XM_006501836
RefSeq - XM_006501838
RefSeq - XM_006501839
RefSeq - XM_006501841
RefSeq - XM_017319677
RefSeq Peptide - NP_001240667
RefSeq Peptide - NP_001258693
RefSeq Peptide - NP_001280677
RefSeq Peptide - NP_001280678
RefSeq Peptide - NP_001344510
RefSeq Peptide - NP_071709
RefSeq Peptide - NP_001240669
swissprot - A0A0R4J1P2
swissprot - P21107
swissprot - Q58E70
swissprot - E9Q7Q3
swissprot - E9Q5J9
swissprot - D3Z6I8
swissprot - D3YVR0
swissprot - A0A1C7ZMY7
Ensembl - ENSMUSG00000027940
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpm3ENSDARG00000005162Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tpm1 / P58771 / tropomyosin 1, alpha / P09493* / tropomyosin 1*ENSMUSG0000003236679
Tpm3-rs7ENSMUSG0000005812677
Tpm2 / P58774 / tropomyosin 2, beta / P07951* / tropomyosin 2*ENSMUSG0000002846473
Tpm4 / Q6IRU2 / Tropomyosin alpha-4 chain / P67936* / tropomyosin 4*ENSMUSG0000003179958


Protein motifs (from Interpro)
Interpro ID Name
 IPR000533  Tropomyosin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 cellular_componentGO:0001725 stress fiber ISO
 cellular_componentGO:0002102 podosome IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005862 muscle thin filament tropomyosin IBA
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0030863 cortical cytoskeleton IDA
 cellular_componentGO:0031941 filamentous actin IDA
 cellular_componentGO:0032154 cleavage furrow IDA
 cellular_componentGO:0043005 neuron projection IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008307 structural constituent of muscle IBA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002108 abnormal muscle morphology "abnormal development of muscle tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0005620 abnormal muscle contractility "aberrant ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

Allelic Composition: Tpm3tm4.1Pgun/Tpm3tm4.1Pgun
Genetic Background: B6JArc.Cg-Tpm3tm4.1Pgun

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Arnttm1Bra/Arnttm1Bra
Genetic Background: B6.129-Arnttm1Bra

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr