ENSMUSG00000031799


Mus musculus

Features
Gene ID: ENSMUSG00000031799
  
Biological name :Tpm4
  
Synonyms : Q6IRU2 / Tpm4 / Tropomyosin alpha-4 chain
  
Possible biological names infered from orthology : P67936 / tropomyosin 4
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 72134975
Gene end: 72153142
  
Corresponding Affymetrix probe sets: 10448202 (MoGene1.0st)   10572747 (MoGene1.0st)   1433883_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003575
NCBI entrez gene - 326618     See in Manteia.
MGI - MGI:2449202
RefSeq - NM_001001491
RefSeq Peptide - NP_001001491
swissprot - Q6IRU2
Ensembl - ENSMUSG00000031799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpm4aENSDARG00000023963Danio rerio
 tpm4bENSDARG00000019128Danio rerio
 TPM4ENSGALG00000002563Gallus gallus
 TPM4ENSG00000167460Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tpm1 / P58771 / tropomyosin 1, alpha / P09493* / tropomyosin 1*ENSMUSG0000003236673
Tpm2 / P58774 / tropomyosin 2, beta / P07951* / tropomyosin 2*ENSMUSG0000002846469
Tpm3-rs7ENSMUSG0000005812667
Tpm3 / P21107 / tropomyosin 3, gammaENSMUSG0000002794066


Protein motifs (from Interpro)
Interpro ID Name
 IPR000533  Tropomyosin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 cellular_componentGO:0001725 stress fiber ISO
 cellular_componentGO:0002102 podosome IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005862 muscle thin filament tropomyosin IBA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030863 cortical cytoskeleton IDA
 cellular_componentGO:0031941 filamentous actin IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008307 structural constituent of muscle IBA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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