ENSG00000167460


Homo sapiens

Features
Gene ID: ENSG00000167460
  
Biological name :TPM4
  
Synonyms : P67936 / TPM4 / tropomyosin 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.12
Gene start: 16067021
Gene end: 16103005
  
Corresponding Affymetrix probe sets: 1567107_s_at (Human Genome U133 Plus 2.0 Array)   209344_at (Human Genome U133 Plus 2.0 Array)   212481_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467558
Ensembl peptide - ENSP00000300933
Ensembl peptide - ENSP00000345230
Ensembl peptide - ENSP00000466106
Ensembl peptide - ENSP00000466158
Ensembl peptide - ENSP00000466654
Ensembl peptide - ENSP00000467087
Ensembl peptide - ENSP00000467250
Ensembl peptide - ENSP00000467319
Ensembl peptide - ENSP00000468246
Ensembl peptide - ENSP00000494125
Ensembl peptide - ENSP00000494589
Ensembl peptide - ENSP00000494867
Ensembl peptide - ENSP00000495135
Ensembl peptide - ENSP00000495347
Ensembl peptide - ENSP00000495506
Ensembl peptide - ENSP00000496389
Ensembl peptide - ENSP00000496574
Ensembl peptide - ENSP00000496648
NCBI entrez gene - 7171     See in Manteia.
OMIM - 600317
RefSeq - XM_011528232
RefSeq - XM_017027189
RefSeq - NM_001145160
RefSeq - NM_003290
RefSeq - XM_005260042
RefSeq - XM_006722865
RefSeq - XM_011528231
RefSeq - XM_017027188
RefSeq Peptide - NP_001138632
RefSeq Peptide - NP_003281
swissprot - V9HW56
swissprot - K7ELJ3
swissprot - K7ELP0
swissprot - K7EMU5
swissprot - K7ENT6
swissprot - K7EP68
swissprot - K7EPB9
swissprot - K7ERG3
swissprot - K7EPV9
swissprot - P67936
Ensembl - ENSG00000167460
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpm4aENSDARG00000023963Danio rerio
 tpm4bENSDARG00000019128Danio rerio
 TPM4ENSGALG00000002563Gallus gallus
 Tpm4ENSMUSG00000031799Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TPM1 / P09493 / tropomyosin 1ENSG0000014041682
TPM3 / P06753 / tropomyosin 3ENSG0000014354981
TPM2 / P07951 / tropomyosin 2ENSG0000019846781


Protein motifs (from Interpro)
Interpro ID Name
 IPR000533  Tropomyosin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0030049 muscle filament sliding TAS
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0002102 podosome IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton TAS
 cellular_componentGO:0005862 muscle thin filament tropomyosin TAS
 cellular_componentGO:0005884 actin filament IBA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030863 cortical cytoskeleton IDA
 cellular_componentGO:0031941 filamentous actin IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008307 structural constituent of muscle TAS
 molecular_functionGO:0042802 identical protein binding ISS
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISS
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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