ENSMUSG00000028466


Mus musculus

Features
Gene ID: ENSMUSG00000028466
  
Biological name :Creb3
  
Synonyms : cAMP responsive element binding protein 3 / Creb3
  
Possible biological names infered from orthology : O43889
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 43562332
Gene end: 43567060
  
Corresponding Affymetrix probe sets: 10504349 (MoGene1.0st)   1419979_s_at (Mouse Genome 430 2.0 Array)   1424740_at (Mouse Genome 430 2.0 Array)   1424741_s_at (Mouse Genome 430 2.0 Array)   1424742_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100008
Ensembl peptide - ENSMUSP00000129401
Ensembl peptide - ENSMUSP00000123831
NCBI entrez gene - 12913     See in Manteia.
MGI - MGI:99946
RefSeq - NM_013497
RefSeq Peptide - NP_038525
swissprot - E9PW77
swissprot - E0CYW8
swissprot - Q3UNH6
Ensembl - ENSMUSG00000028466
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 creb3l3lENSDARG00000020926Danio rerio
 CREB3ENSGALG00000002523Gallus gallus
 CREB3ENSG00000107175Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91XE9 / Creb3l3 / Cyclic AMP-responsive element-binding protein 3-like protein 3 Processed cyclic AMP-responsive element-binding protein 3-like protein 3 / Q68CJ9* / cAMP responsive elemen...ENSMUSG0000003504132
Q8BH52 / Creb3l2 / Cyclic AMP-responsive element-binding protein 3-like protein 2 Processed cyclic AMP-responsive element-binding protein 3-like protein 2 / Q70SY1* / cAMP responsive elemen...ENSMUSG0000003864825
Q9D2A5 / Creb3l4 / Cyclic AMP-responsive element-binding protein 3-like protein 4 Processed cyclic AMP-responsive element-binding protein 3-like protein 4 / Q8TEY5* / cAMP responsive elemen...ENSMUSG0000002793825
Creb3l1 / cAMP responsive element binding protein 3 like 1 / Q96BA8*ENSMUSG0000002723023


Protein motifs (from Interpro)
Interpro ID Name
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029808  cAMP-responsive element-binding protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response IEA
 biological_processGO:0030968 endoplasmic reticulum unfolded protein response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IEA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0035497 cAMP response element binding IEA


Pathways (from Reactome)
Pathway description
CREB3 factors activate genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031835 Mbtps1 / Q9WTZ2 / Membrane-bound transcription factor site-1 protease / Q14703* / membrane bound transcription factor peptidase, site 1*  / reaction
 ENSMUSG00000048249 Crebrf / Q8CDG5 / CREB3 regulatory factor / Q8IUR6*  / reaction / complex






 

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