ENSMUSG00000028759


Mus musculus

Features
Gene ID: ENSMUSG00000028759
  
Biological name :Hp1bp3
  
Synonyms : Hp1bp3 / Mus musculus heterochromatin protein 1, binding protein 3 (Hp1bp3), transcript variant 9, mRNA. / Q3TEA8
  
Possible biological names infered from orthology : heterochromatin protein 1 binding protein 3 / Q5SSJ5
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 138216296
Gene end: 138244683
  
Corresponding Affymetrix probe sets: 10509500 (MoGene1.0st)   10338180 (MoGene1.0st)   10339177 (MoGene1.0st)   10339374 (MoGene1.0st)   10339657 (MoGene1.0st)   10340721 (MoGene1.0st)   10340971 (MoGene1.0st)   10342171 (MoGene1.0st)   10342502 (MoGene1.0st)   10342675 (MoGene1.0st)   10342747 (MoGene1.0st)   10343067 (MoGene1.0st)   10343379 (MoGene1.0st)   10344028 (MoGene1.0st)   10344363 (MoGene1.0st)   10344447 (MoGene1.0st)   10338145 (MoGene1.0st)   10338476 (MoGene1.0st)   10338575 (MoGene1.0st)   10338797 (MoGene1.0st)   10339158 (MoGene1.0st)   10339305 (MoGene1.0st)   10339562 (MoGene1.0st)   10339606 (MoGene1.0st)   10339978 (MoGene1.0st)   10340128 (MoGene1.0st)   10340224 (MoGene1.0st)   10340260 (MoGene1.0st)   10340265 (MoGene1.0st)   10340501 (MoGene1.0st)   10340826 (MoGene1.0st)   10340996 (MoGene1.0st)   10341447 (MoGene1.0st)   10341502 (MoGene1.0st)   10341577 (MoGene1.0st)   10341726 (MoGene1.0st)   10342328 (MoGene1.0st)   10342521 (MoGene1.0st)   10342705 (MoGene1.0st)   10342850 (MoGene1.0st)   10342932 (MoGene1.0st)   10343226 (MoGene1.0st)   10343272 (MoGene1.0st)   10343831 (MoGene1.0st)   10343873 (MoGene1.0st)   10343875 (MoGene1.0st)   10344273 (MoGene1.0st)   10344316 (MoGene1.0st)   1415751_at (Mouse Genome 430 2.0 Array)   1439845_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118913
Ensembl peptide - ENSMUSP00000117216
Ensembl peptide - ENSMUSP00000120587
Ensembl peptide - ENSMUSP00000132614
Ensembl peptide - ENSMUSP00000123467
Ensembl peptide - ENSMUSP00000122005
Ensembl peptide - ENSMUSP00000030541
Ensembl peptide - ENSMUSP00000095447
Ensembl peptide - ENSMUSP00000101451
Ensembl peptide - ENSMUSP00000101452
Ensembl peptide - ENSMUSP00000101453
NCBI entrez gene - 15441     See in Manteia.
MGI - MGI:109369
RefSeq - NM_001285480
RefSeq - NM_001122896
RefSeq - NM_001122897
RefSeq - NM_001285478
RefSeq - NM_001285479
RefSeq - NM_001285481
RefSeq - NM_001356431
RefSeq - NM_001356432
RefSeq - NM_010470
RefSeq - XM_006538565
RefSeq - XM_006538566
RefSeq - XM_006538567
RefSeq - XM_006538568
RefSeq - XM_006538570
RefSeq - XM_017319985
RefSeq Peptide - NP_001116368
RefSeq Peptide - NP_001272407
RefSeq Peptide - NP_001272408
RefSeq Peptide - NP_001272409
RefSeq Peptide - NP_001272410
RefSeq Peptide - NP_001343360
RefSeq Peptide - NP_001343361
RefSeq Peptide - NP_034600
RefSeq Peptide - NP_001116369
swissprot - Q3TEA8
swissprot - Z4YKA3
swissprot - A2AM70
swissprot - A2AM69
swissprot - A2AM65
swissprot - A2AM63
swissprot - A2AM62
swissprot - Z4YKB8
Ensembl - ENSMUSG00000028759
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hp1bp3ENSDARG00000044669Danio rerio
 HP1BP3ENSGALG00000010079Gallus gallus
 HP1BP3ENSG00000127483Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H1foo / Q8VIK3 / Mus musculus H1 histone family, member O, oocyte-specific (H1foo), transcript variant 2, mRNA. / Q8IZA3* / H1 histone family member O oocyte specific*ENSMUSG0000004227912


Protein motifs (from Interpro)
Interpro ID Name
 IPR005818  Linker histone H1/H5, domain H15
 IPR005819  Histone H5
 IPR033061  Heterochromatin protein 1-binding protein 3
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISO
 biological_processGO:0042127 regulation of cell proliferation ISO
 biological_processGO:0070828 heterochromatin organization ISO
 biological_processGO:0071456 cellular response to hypoxia ISS
 biological_processGO:0097298 regulation of nucleus size ISO
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome ISO
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0031491 nucleosome binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Trp53tm3Tyj/Trp53+,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

Allelic Composition: Hp1bp3tm1a(EUCOMM)Wtsi/Hp1bp3+
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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