ENSMUSG00000028821


Mus musculus

Features
Gene ID: ENSMUSG00000028821
  
Biological name :Syf2
  
Synonyms : Pre-mRNA-splicing factor SYF2 / Q9D198 / Syf2
  
Possible biological names infered from orthology : O95926 / SYF2 pre-mRNA splicing factor
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 134930898
Gene end: 134937548
  
Corresponding Affymetrix probe sets: 10509023 (MoGene1.0st)   1424104_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030622
NCBI entrez gene - 68592     See in Manteia.
MGI - MGI:1915842
RefSeq - NM_026780
RefSeq Peptide - NP_081056
swissprot - Q9D198
Ensembl - ENSMUSG00000028821
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syf2ENSDARG00000004706Danio rerio
 SYF2ENSGALG00000013639Gallus gallus
 SYF2ENSG00000117614Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013260  mRNA splicing factor SYF2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint IMP
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0048568 embryonic organ development IMP
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071007 U2-type catalytic step 2 spliceosome IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 cellular_componentGO:0071014 post-mRNA release spliceosomal complex IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001696 failure to gastrulate "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]
Show

Allelic Composition: Crybb2Lop19/Crybb2+
Genetic Background: SJL/J-Crybb2Lop19/BocJ

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Crybb2Lop19/Crybb2+
Genetic Background: SJL/J-Crybb2Lop19/BocJ

 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Crybb2Lop19/Crybb2+
Genetic Background: SJL/J-Crybb2Lop19/BocJ

 MP:0004045 abnormal cell cycle checkpoint function "anomaly in the amount of time spent at the points in the cell cycle (end of G1 phase, end of G2 phase, and during metaphase) which prevent the cell from progressing to the next phase when conditions are unfavorable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Crybb2Lop19/Crybb2+
Genetic Background: SJL/J-Crybb2Lop19/BocJ

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Crybb2Lop19/Crybb2+
Genetic Background: SJL/J-Crybb2Lop19/BocJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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