ENSMUSG00000029146


Mus musculus

Features
Gene ID: ENSMUSG00000029146
  
Biological name :Snx17
  
Synonyms : Q8BVL3 / Snx17 / Sorting nexin-17
  
Possible biological names infered from orthology : Q15036
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B1
Gene start: 31193227
Gene end: 31199143
  
Corresponding Affymetrix probe sets: 10520718 (MoGene1.0st)   1455955_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144504
Ensembl peptide - ENSMUSP00000144688
Ensembl peptide - ENSMUSP00000144643
Ensembl peptide - ENSMUSP00000031029
Ensembl peptide - ENSMUSP00000144168
NCBI entrez gene - 266781     See in Manteia.
MGI - MGI:2387801
RefSeq - XM_011240733
RefSeq - NM_153680
RefSeq Peptide - NP_710147
swissprot - H3BKQ6
swissprot - D3Z3J1
swissprot - D3Z7S9
swissprot - Q8BVL3
swissprot - H3BKG9
Ensembl - ENSMUSG00000029146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx17ENSDARG00000091418Danio rerio
 SNX17ENSGALG00000032468Gallus gallus
 SNX17ENSG00000115234Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snx31 / Q6P8Y7 / Mus musculus sorting nexin 31 (Snx31), transcript variant 2, mRNA. / Q8N9S9* / sorting nexin 31*ENSMUSG0000001361136
Snx27 / Q3UHD6 / Sorting nexin-27 / Q96L92* / sorting nexin family member 27*ENSMUSG0000002813620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000299  FERM domain
 IPR001683  Phox homologous domain
 IPR028666  Sorting nexin-17
 IPR036871  PX domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003279 cardiac septum development IMP
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006898 receptor-mediated endocytosis IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0035904 aorta development IMP
 biological_processGO:0060976 coronary vasculature development IMP
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000273 overriding aorta "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]
Show

Allelic Composition: Alx3tm1Hubr/Alx3tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
Show

Allelic Composition: Alx3tm1Hubr/Alx3tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001293 anophthalmia "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]
Show

Allelic Composition: Alx3tm1Hubr/Alx3tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0010412 atrioventricular septal defect "defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)" [http://emedicine.medscape.com]
Show

Allelic Composition: Alx3tm1Hubr/Alx3tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011661 persistent truncus arteriosus type i "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development; type i is characterized by origin of a single pulmonary trunk from the left lateral aspect of the common trunk, with branching of the left and right pulmonary arteries from the pulmonary trunk" [http://emedicine.medscape.com]
Show

Allelic Composition: Alx3tm1Hubr/Alx3tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr