ENSMUSG00000029403


Mus musculus

Features
Gene ID: ENSMUSG00000029403
  
Biological name :Cdkl2
  
Synonyms : Cdkl2 / Cyclin-dependent kinase-like 2 / Q9QUK0
  
Possible biological names infered from orthology : Q92772
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E2
Gene start: 92006074
Gene end: 92043883
  
Corresponding Affymetrix probe sets: 10531304 (MoGene1.0st)   1441820_at (Mouse Genome 430 2.0 Array)   1449229_a_at (Mouse Genome 430 2.0 Array)   1457625_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000084199
Ensembl peptide - ENSMUSP00000108768
Ensembl peptide - ENSMUSP00000143967
Ensembl peptide - ENSMUSP00000063617
Ensembl peptide - ENSMUSP00000108765
NCBI entrez gene - 53886     See in Manteia.
MGI - MGI:1858227
RefSeq - XM_017320989
RefSeq - NM_001276315
RefSeq - NM_016912
RefSeq - NM_177270
RefSeq - XM_011249537
RefSeq - XM_011249538
RefSeq - XM_011249539
RefSeq - XM_017320987
RefSeq - XM_017320988
RefSeq Peptide - NP_001263244
RefSeq Peptide - NP_058608
RefSeq Peptide - NP_796244
swissprot - A0A0J9YU22
swissprot - Q149A0
swissprot - Q9QUK0
Ensembl - ENSMUSG00000029403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDKL2ENSGALG00000010119Gallus gallus
 CDKL2ENSG00000138769Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdkl3 / Q8BLF2 / Cyclin-dependent kinase-like 3 / Q8IVW4*ENSMUSG0000002038941
Cdkl5 / Q3UTQ8 / Cyclin-dependent kinase-like 5 / O76039*ENSMUSG0000003129233
Cdkl1 / Q8CEQ0 / Cyclin-dependent kinase-like 1 / Q00532*ENSMUSG0000002099031
Cdkl4 / Q3TZA2 / Cyclin-dependent kinase-like 4 / Q5MAI5*ENSMUSG0000003396631
Cdk20 / Q9JHU3 / Cyclin-dependent kinase 20 / Q8IZL9*ENSMUSG0000002148321
Cdk7 / Q03147 / Cyclin-dependent kinase 7 / P50613*ENSMUSG0000006908920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Arf4tm1b(KOMP)Wtsi/Arf4tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Arf4tm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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