ENSG00000138769


Homo sapiens

Features
Gene ID: ENSG00000138769
  
Biological name :CDKL2
  
Synonyms : CDKL2 / cyclin dependent kinase like 2 / Q92772
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.1
Gene start: 75578005
Gene end: 75630716
  
Corresponding Affymetrix probe sets: 207073_at (Human Genome U133 Plus 2.0 Array)   236331_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412365
Ensembl peptide - ENSP00000422666
Ensembl peptide - ENSP00000306340
NCBI entrez gene - 8999     See in Manteia.
OMIM - 603442
RefSeq - XM_017008811
RefSeq - NM_003948
RefSeq - XM_005263335
RefSeq - XM_006714406
RefSeq - XM_017008809
RefSeq - XM_017008810
RefSeq Peptide - NP_001317653
RefSeq Peptide - NP_003939
swissprot - Q92772
swissprot - D6RBJ5
swissprot - J3KNE8
swissprot - A0A140VJG1
Ensembl - ENSG00000138769
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDKL2ENSGALG00000010119Gallus gallus
 Cdkl2ENSMUSG00000029403Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDKL3 / Q8IVW4 / cyclin dependent kinase like 3ENSG0000000683740
CDKL5 / O76039 / cyclin dependent kinase like 5ENSG0000000808635
CDKL1 / Q00532 / cyclin dependent kinase like 1ENSG0000010049033
CDKL4 / Q5MAI5 / cyclin dependent kinase like 4ENSG0000020511129
CDK20 / Q8IZL9 / cyclin dependent kinase 20ENSG0000015634521
CDK7 / P50613 / cyclin dependent kinase 7ENSG0000013405820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007548 sex differentiation TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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