ENSG00000006837


Homo sapiens

Features
Gene ID: ENSG00000006837
  
Biological name :CDKL3
  
Synonyms : CDKL3 / cyclin dependent kinase like 3 / Q8IVW4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.1
Gene start: 134286350
Gene end: 134371047
  
Corresponding Affymetrix probe sets: 1561190_at (Human Genome U133 Plus 2.0 Array)   219831_at (Human Genome U133 Plus 2.0 Array)   236017_at (Human Genome U133 Plus 2.0 Array)   241911_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427964
Ensembl peptide - ENSP00000427836
Ensembl peptide - ENSP00000428498
Ensembl peptide - ENSP00000430777
Ensembl peptide - ENSP00000430496
Ensembl peptide - ENSP00000428689
Ensembl peptide - ENSP00000428500
Ensembl peptide - ENSP00000265334
Ensembl peptide - ENSP00000427738
NCBI entrez gene - 51265     See in Manteia.
OMIM - 608459
RefSeq - XM_017009548
RefSeq - XM_017009536
RefSeq - XM_017009537
RefSeq - XM_017009538
RefSeq - XM_017009539
RefSeq - XM_017009540
RefSeq - XM_017009541
RefSeq - XM_017009542
RefSeq - XM_017009543
RefSeq - XM_017009544
RefSeq - XM_017009545
RefSeq - XM_017009546
RefSeq - NM_001113575
RefSeq - NM_001300853
RefSeq - NM_016508
RefSeq - XM_011543429
RefSeq - XM_011543439
RefSeq - XM_011543444
RefSeq - XM_017009524
RefSeq - XM_017009525
RefSeq - XM_017009526
RefSeq - XM_017009527
RefSeq - XM_017009528
RefSeq - XM_017009529
RefSeq - XM_017009530
RefSeq - XM_017009531
RefSeq - XM_017009532
RefSeq - XM_017009533
RefSeq - XM_017009534
RefSeq - XM_017009535
RefSeq Peptide - NP_057592
RefSeq Peptide - NP_001107047
RefSeq Peptide - NP_001287782
swissprot - E5RFT9
swissprot - H0YAP8
swissprot - E7ET86
swissprot - Q8IVW4
swissprot - B4DX41
swissprot - H0YB17
swissprot - E5RI54
swissprot - E5RGK4
Ensembl - ENSG00000006837
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cdkl3ENSMUSG00000020389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDKL2 / Q92772 / cyclin dependent kinase like 2ENSG0000013876939
CDKL5 / O76039 / cyclin dependent kinase like 5ENSG0000000808629
CDKL1 / Q00532 / cyclin dependent kinase like 1ENSG0000010049026
CDKL4 / Q5MAI5 / cyclin dependent kinase like 4ENSG0000020511126
CDK7 / P50613 / cyclin dependent kinase 7ENSG0000013405818
CDK20 / Q8IZL9 / cyclin dependent kinase 20ENSG0000015634518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030517 negative regulation of axon extension IBA
 biological_processGO:0050775 positive regulation of dendrite morphogenesis IBA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0097484 dendrite extension IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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