ENSG00000100490


Homo sapiens

Features
Gene ID: ENSG00000100490
  
Biological name :CDKL1
  
Synonyms : CDKL1 / cyclin dependent kinase like 1 / Q00532
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q22.1
Gene start: 50329404
Gene end: 50416461
  
Corresponding Affymetrix probe sets: 1555286_at (Human Genome U133 Plus 2.0 Array)   207766_at (Human Genome U133 Plus 2.0 Array)   235512_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216378
Ensembl peptide - ENSP00000379176
Ensembl peptide - ENSP00000431449
Ensembl peptide - ENSP00000435044
NCBI entrez gene - 8814     See in Manteia.
OMIM - 603441
RefSeq - XM_017021732
RefSeq - XM_005268157
RefSeq - XM_005268159
RefSeq - XM_011537276
RefSeq - XM_017021729
RefSeq - XM_017021730
RefSeq - XM_017021731
RefSeq - NM_001282236
RefSeq - NM_004196
RefSeq Peptide - NP_001269165
RefSeq Peptide - NP_004187
swissprot - H0YE65
swissprot - J3KMW1
swissprot - Q00532
swissprot - H0YCE5
Ensembl - ENSG00000100490
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdkl1ENSDARG00000017329Danio rerio
 CDKL1ENSGALG00000012295Gallus gallus
 Cdkl1ENSMUSG00000020990Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDKL4 / Q5MAI5 / cyclin dependent kinase like 4ENSG0000020511160
CDKL2 / Q92772 / cyclin dependent kinase like 2ENSG0000013876952
CDKL5 / O76039 / cyclin dependent kinase like 5ENSG0000000808644
CDKL3 / Q8IVW4 / cyclin dependent kinase like 3ENSG0000000683743
CDK20 / Q8IZL9 / cyclin dependent kinase 20ENSG0000015634534
CDK7 / P50613 / cyclin dependent kinase 7ENSG0000013405833


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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