Manteia - Molecule gene

ENSMUSG00000029843

Mus musculus

Features

Gene ID:	ENSMUSG00000029843

Biological name :	Slc13a4

Synonyms :	Slc13a4 / solute carrier family 13 member 4

Possible biological names infered from orthology :	Q9UKG4

Species:	Mus musculus

Chr. number:	6
Strand:	-1
Band:	B1
Gene start:	35267957
Gene end:	35308131

Corresponding Affymetrix probe sets:	10543921 (MoGene1.0st) 1433734_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000031868 NCBI entrez gene - 243755 See in Manteia. MGI - MGI:2442367 RefSeq - NM_172892 RefSeq Peptide - NP_766480 swissprot - Q8BZ82 Ensembl - ENSMUSG00000029843

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
slc13a4	ENSDARG00000059053	Danio rerio
SLC13A4	ENSGALG00000012908	Gallus gallus
Q9UKG4	ENSG00000164707	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9JHI4 / Slc13a1 / Solute carrier family 13 member 1 / Q9BZW2*	ENSMUSG00000029700	48
Q9ES88 / Slc13a2 / Solute carrier family 13 member 2 / Q13183*	ENSMUSG00000001095	39
Q67BT3 / Slc13a5 / Solute carrier family 13 member 5 / Q86YT5*	ENSMUSG00000020805	37
Q91Y63 / Slc13a3 / solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 / Q8WWT9* / solute carrier family 13 member 3*	ENSMUSG00000018459	37

Protein motifs (from Interpro)

Interpro ID	Name
IPR001898	Solute carrier family 13

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006814	sodium ion transport	IEA
biological_process	GO:0008272	sulfate transport	IBA
biological_process	GO:0055085	transmembrane transport	IEA
biological_process	GO:0098656	anion transmembrane transport	IBA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005215	transporter activity	IBA

Pathways (from Reactome)

Pathway description

Sodium-coupled sulphate, di- and tri-carboxylate transporters

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0000192	abnormal mineral level	"anomalous concentration of any inorganic substance that has importance in body functions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0000428	abnormal craniofacial morphology	"anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0001303	abnormal lens morphology	"malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0001914	hemorrhage	"loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0003717	pallor	"an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0004265	abnormal placental transport	"anomaly in the conveyance of metabolic products and nutrients across the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0004624	abnormal thoracic cage	"any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0005262	coloboma	"anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0008274	failure of bone ossification	"failure to initiate or a block in the process of the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0009577	abnormal developmental vascular remodeling	"any anomaly in the process by which existing vessels are reorganized during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0009653	abnormal palate development	"abnormal formation of the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0010714	coloboma of the iris	"congenital defect of the iris in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0011099	complete lethality throughout fetal growth and development	"death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac Allelic Composition: Slc13a4^{tm1c(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi},Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Slc13a4^{tm1d(EUCOMM)Wtsi}/Slc13a4^{tm1d(EUCOMM)Wtsi} Genetic Background: involves: C57BL/6 * CBA
MP:0013848	subcutaneous edema	"accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith]	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac
MP:0020137	decreased bone mineralization	"decrease in the rate at which minerals are deposited into bone" []	Show Allelic Composition: Kcnu1^tm1.1Clin/Kcnu1⁺ Genetic Background: involves: C57BL/6NTac

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr