ENSMUSG00000029700


Mus musculus

Features
Gene ID: ENSMUSG00000029700
  
Biological name :Slc13a1
  
Synonyms : Q9JHI4 / Slc13a1 / Solute carrier family 13 member 1
  
Possible biological names infered from orthology : Q9BZW2
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: A3.1
Gene start: 24088283
Gene end: 24168092
  
Corresponding Affymetrix probe sets: 10543411 (MoGene1.0st)   1430804_at (Mouse Genome 430 2.0 Array)   1431379_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031713
NCBI entrez gene - 55961     See in Manteia.
MGI - MGI:1859937
RefSeq - NM_019481
RefSeq Peptide - NP_062354
swissprot - Q9JHI4
Ensembl - ENSMUSG00000029700
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc13a1ENSDARG00000045638Danio rerio
 SLC13A1ENSGALG00000008874Gallus gallus
 Q9BZW2ENSG00000081800Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slc13a4 / solute carrier family 13 member 4 / Q9UKG4*ENSMUSG0000002984351
Q9ES88 / Slc13a2 / Solute carrier family 13 member 2 / Q13183*ENSMUSG0000000109540
Q67BT3 / Slc13a5 / Solute carrier family 13 member 5 / Q86YT5*ENSMUSG0000002080539
Q91Y63 / Slc13a3 / solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 / Q8WWT9* / solute carrier family 13 member 3*ENSMUSG0000001845938


Protein motifs (from Interpro)
Interpro ID Name
 IPR001898  Solute carrier family 13
 IPR031312  Sodium/sulphate symporter, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0008272 sulfate transport IDA
 biological_processGO:0035725 sodium ion transmembrane transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902358 sulfate transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0008271 secondary active sulfate transmembrane transporter activity IDA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015382 sodium:sulfate symporter activity IEA


Pathways (from Reactome)
Pathway description
Sodium-coupled sulphate, di- and tri-carboxylate transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002853 hyposulfatemia "abnormally low concentration of sulfate in the circulating blood" [J:86561]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003996 clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by unilateral or bilateral rhythmic jerking movements of the arms and legs caused by alternating contraction and relaxation of muscle" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

 MP:0004244 abnormal spontaneous abortion rate "change in frequency of a natural or accidental termination of a pregnancy at a stage where the embryo or the fetus is incapable of surviving independently of the mother" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004701 decreased circulating insulin-like growth factor I level "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004789 increased bile salt level "increased concentration of the steroid salts derived from cholesterol in the liver, produced as bile acids and secreted in the biliary sytem as bile salts; these play an important role in the digestion and absorption of fats" [MESH:D04.808.105, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

 MP:0009472 hypersulfaturia "an increase of excretion of sulfates in the urine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

 MP:0010107 abnormal renal reabsorption "any anomaly in the two-step process beginning with the active or passive extraction of substances (such as water, glucose, oligopeptides, amino acids, sodium (Na+) and other ions) from the renal tubule fluid into the renal interstitium, and the subsequent transport of these substances out of the renal interstitium back into the bloodstream; reabsorption begins in the proximal convoluted tubules and continues in the loop of Henle, distal convoluted tubules, and collecting tubules" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Slc13a1tm1Mark/Slc13a1+
Genetic Background: involves: 129T2/SvEms * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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