ENSMUSG00000030435


Mus musculus

Features
Gene ID: ENSMUSG00000030435
  
Biological name :U2af2
  
Synonyms : P26369 / U2af2 / U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
  
Possible biological names infered from orthology : P26368 / U2 small nuclear RNA auxiliary factor 2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A1
Gene start: 5062143
Gene end: 5079938
  
Corresponding Affymetrix probe sets: 10549770 (MoGene1.0st)   1417260_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000005041
Ensembl peptide - ENSMUSP00000147013
Ensembl peptide - ENSMUSP00000147032
Ensembl peptide - ENSMUSP00000147246
Ensembl peptide - ENSMUSP00000131458
NCBI entrez gene - 22185     See in Manteia.
MGI - MGI:98886
RefSeq - XM_017322124
RefSeq - NM_001205231
RefSeq - NM_133671
RefSeq - XM_006539727
RefSeq - XM_006539728
RefSeq - XM_006539730
RefSeq Peptide - NP_001192160
RefSeq Peptide - NP_598432
swissprot - A0A140LJK3
swissprot - P26369
swissprot - A0A140LJ08
swissprot - Q80XR5
swissprot - Q3KQM4
Ensembl - ENSMUSG00000030435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 u2af2aENSDARG00000012505Danio rerio
 u2af2bENSDARG00000011740Danio rerio
 U2AF2ENSG00000063244Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Uhmk1 / P97343 / U2AF homology motif (UHM) kinase 1 / Q8TAS1* / U2AF homology motif kinase 1*ENSMUSG0000002666716


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR006529  U2 snRNP auxilliary factor, large subunit, splicing factor
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0033120 positive regulation of RNA splicing IEA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IEA
 biological_processGO:1903146 regulation of autophagy of mitochondrion ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0000243 commitment complex IBA
 cellular_componentGO:0000974 Prp19 complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071004 U2-type prespliceosome IEA
 cellular_componentGO:0089701 U2AF IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008187 poly-pyrimidine tract binding IBA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030628 pre-mRNA 3"-splice site binding IEA
 molecular_functionGO:0070742 C2H2 zinc finger domain binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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